Literature DB >> 9393835

CD8+ T cells are activated during the early Th1 and Th2 immune responses in a murine Lyme disease model.

Z Dong1, M D Edelstein, L J Glickstein.   

Abstract

T-helper responses following Borrelia burgdorferi infection in mice determine susceptibility to Lyme arthritis. The ratio of interleukin 4-positive, CD4+ to gamma interferon (IFN-gamma)-positive, CD4+ T cells was significantly greater in infected BALB/cJ mice than in infected C3H/HeJ mice. Increased numbers of IFN-gamma-producing cells predicted greater arthritis severity, and CD8+ T cells were the main source of IFN-gamma in both strains.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9393835      PMCID： PMC175768          DOI： 10.1128/iai.65.12.5334-5337.1997

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  34 in total

1.  Infectivity of Borrelia burgdorferi relative to route of inoculation and genotype in laboratory mice.

Authors:  S W Barthold
Journal:  J Infect Dis       Date:  1991-02       Impact factor: 5.226

2.  Common themes amid diversity.

Authors:  S Normark; H Wolf-Watz
Journal:  Science       Date:  1997-05-02       Impact factor: 47.728

3.  Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system.

Authors:  H S Panitch; R L Hirsch; J Schindler; K P Johnson
Journal:  Neurology       Date:  1987-07       Impact factor: 9.910

4.  Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice.

Authors:  L Yang; Y Ma; R Schoenfeld; M Griffiths; E Eichwald; B Araneo; J J Weis
Journal:  Infect Immun       Date:  1992-08       Impact factor: 3.441

5.  Lyme borreliosis in selected strains and ages of laboratory mice.

Authors:  S W Barthold; D S Beck; G M Hansen; G A Terwilliger; K D Moody
Journal:  J Infect Dis       Date:  1990-07       Impact factor: 5.226

Review 6.  Lyme disease.

Authors:  A C Steere
Journal:  N Engl J Med       Date:  1989-08-31       Impact factor: 91.245

7.  Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis.

Authors:  F P Heinzel; M D Sadick; S S Mutha; R M Locksley
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-15       Impact factor: 11.205

8.  Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice.

Authors:  U E Schaible; M D Kramer; K Eichmann; M Modolell; C Museteanu; M M Simon
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

9.  Experimental Borrelia burgdorferi infection in inbred mouse strains: antibody response and association of H-2 genes with resistance and susceptibility to development of arthritis.

Authors:  U E Schaible; M D Kramer; R Wallich; T Tran; M M Simon
Journal:  Eur J Immunol       Date:  1991-10       Impact factor: 5.532

10.  Borrelia burgdorferi activates a T helper type 1-like T cell subset in Lyme arthritis.

Authors:  H Yssel; M C Shanafelt; C Soderberg; P V Schneider; J Anzola; G Peltz
Journal:  J Exp Med       Date:  1991-09-01       Impact factor: 14.307
View more
  8 in total

1.  Acquired immunity to Chlamydia pneumoniae is dependent on gamma interferon in two mouse strains that initially differ in this respect after primary challenge.

Authors:  J M Vuola; V Puurula; M Anttila; P H Mäkelä; N Rautonen
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

Review 2.  Lyme arthritis: current concepts and a change in paradigm.

Authors:  Dean T Nardelli; Steven M Callister; Ronald F Schell
Journal:  Clin Vaccine Immunol       Date:  2007-11-14

3.  Activation of endothelium by Borrelia burgdorferi in vitro enhances transmigration of specific subsets of T lymphocytes.

Authors:  E I Gergel; M B Furie
Journal:  Infect Immun       Date:  2001-04       Impact factor: 3.441

4.  Cardiac conduction abnormalities in a mouse model of Lyme borreliosis.

Authors:  S Saba; B A VanderBrink; G Perides; L J Glickstein; M S Link; M K Homoud; R T Bronson; M Estes ; P J Wang
Journal:  J Interv Card Electrophysiol       Date:  2001-06       Impact factor: 1.900

5.  Gamma interferon is not required for arthritis resistance in the murine Lyme disease model.

Authors:  L Glickstein; M Edelstein; J Z Dong
Journal:  Infect Immun       Date:  2001-06       Impact factor: 3.441

Review 6.  Lyme borreliosis in 2005, 30 years after initial observations in Lyme Connecticut.

Authors:  Allen C Steere
Journal:  Wien Klin Wochenschr       Date:  2006-11       Impact factor: 1.704

7.  Phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, potentiates innate immune activation and induces apoptosis in human monocytes.

Authors:  Adriana R Cruz; Meagan W Moore; Carson J La Vake; Christian H Eggers; Juan C Salazar; Justin D Radolf
Journal:  Infect Immun       Date:  2007-10-15       Impact factor: 3.441

8.  IFNgamma production in peripheral blood of early Lyme disease patients to hLFAalphaL (aa326-345).

Authors:  Maria J C Gomes-Solecki; Gary P Wormser; Raymond J Dattwyler
Journal:  BMC Musculoskelet Disord       Date:  2002-10-17       Impact factor: 2.362
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.