Literature DB >> 938697

Regional serotonin levels in brain: a comparison of depressive suicides and alcoholic suicides with controls.

E Cochran, E Robins, S Grote.   

Abstract

The levels of 5-hydroxytryptamine have been measured in 33 areas of the human brain and these levels compared in depressed suicides, in alcoholic suicides, and in controls. The values obtained for control brains ranged from 5.3 mumole 5-HT/kg wet weight in substantia nigra to 0.4 mumole 5-HT/kg wet weight in frontal gray. No significant differences were found among diagnostic groups in any of the areas studied.

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Year:  1976        PMID： 938697

Source DB:  PubMed          Journal:  Biol Psychiatry        ISSN： 0006-3223            Impact factor:   13.382


  11 in total

1.  Effect of aging on lazabemide binding, monoamine oxidase activity and monoamine metabolites in human frontal cortex.

Authors:  M D Galva; G P Bondiolotti; M Olasmaa; G B Picotti
Journal:  J Neural Transm Gen Sect       Date:  1995

2.  Lower 3H-paroxetine binding in cerebral cortex of suicide victims is partly due to fewer high affinity, non-transporter sites.

Authors:  J J Mann; R A Henteleff; T F Lagattuta; J A Perper; S Li; V Arango
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

3.  Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity.

Authors:  C A Stockmeier; L A Shapiro; G E Dilley; T N Kolli; L Friedman; G Rajkowska
Journal:  J Neurosci       Date:  1998-09-15       Impact factor: 6.167

4.  Brain tryptophan metabolism in schizophrenia: a post mortem study of metabolites of the serotonin and kynurenine pathways in schizophrenic and control subjects.

Authors:  M H Jospeh; H F Baker; T J Crow; G J Riley; D Risby
Journal:  Psychopharmacology (Berl)       Date:  1979-04-25       Impact factor: 4.530

5.  Brain monoaminergic and neuropeptidergic variations in human aging.

Authors:  B Arranz; K Blennow; R Ekman; A Eriksson; J E Månsson; J Marcusson
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

6.  Factors influencing monoamine metabolites and tryptophan in patients with alcohol dependence.

Authors:  C M Banki
Journal:  J Neural Transm       Date:  1981       Impact factor: 3.575

7.  Distribution of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in human brain in relation to age, drug influence, agonal status and circadian variation.

Authors:  G Bucht; R Adolfsson; C G Gottfries; B E Roos; B Winblad
Journal:  J Neural Transm       Date:  1981       Impact factor: 3.575

8.  Regional studies of serotonin and dopamine metabolism and quantification of serotonin uptake sites in human cerebral cortex.

Authors:  B Parsons; A Roxas; Y Y Huang; A Dwork; M Stanley
Journal:  J Neural Transm Gen Sect       Date:  1992

9.  Fluvoxamine-a new serotonin re-uptake inhibitor: first clinical and psychometric experiences in depressed patients.

Authors:  B Saletu; M Schjerve; J Grünberger; H Schanda; O H Arnold
Journal:  J Neural Transm       Date:  1977       Impact factor: 3.575

10.  Elevated serotonin and 5-HIAA in the brainstem and lower serotonin turnover in the prefrontal cortex of suicides.

Authors:  Helene Bach; Yung-Yu Huang; Mark D Underwood; Andrew J Dwork; J John Mann; Victoria Arango
Journal:  Synapse       Date:  2013-07-23       Impact factor: 2.562
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