| Literature DB >> 9382823 |
Abstract
The discovery of multiple signaling cascades downstream of Atm may lead to a clearer understanding of the diverse defects seen in ataxia-telangiectasia. These pathways - which include evolutionarily conserved Chk1 and Atr, and non-conserved p21, p53 and AbI - guard genomic integrity after DNA damage.Entities:
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Year: 1997 PMID: 9382823 DOI: 10.1016/s0960-9822(06)00406-4
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834