| Literature DB >> 9377085 |
G H Posner1, P Ploypradith, W Hapangama, D Wang, J N Cumming, P Dolan, T W Kensler, D Klinedinst, T A Shapiro, Q Y Zheng, C K Murray, L G Pilkington, L R Jayasinghe, J F Bray, R Daughenbaugh.
Abstract
A series of tetracyclic and tricyclic trioxane dimers has been prepared with ether and ester tethers of varying length and flexibility. Several of these trioxane dimers have been found to have potent and potentially therapeutically valuable antimalarial, antiproliferative, and antitumor activities in vitro.Entities:
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Year: 1997 PMID： 9377085 DOI： 10.1016/s0968-0896(97)00079-5
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641