Literature DB >> 9376675

The trans-sialidase of Trypanosoma cruzi is anchored by two different lipids.

R Agusti1, A S Couto, O E Campetella, A C Frasch, R M de Lederkremer.   

Abstract

The trans-sialidase from the trypomastigote stage of Trypanosoma cruzi was metabolically labeled with [3H]-palmitic acid and purified by immunoprecipitation with a monoclonal antibody. The action of PI-PLC on the immunoprecipitate released a lipid that was analyzed by TLC. Lyso-1-O-hexadecylglycerol and N-palmitoyl-sphinganine were obtained in a 1:3 ratio. A comparison with the GPI anchors present in the different stages of T. cruzi was made.

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Year:  1997        PMID： 9376675     DOI： 10.1093/glycob/7.6.731

Source DB:  PubMed          Journal:  Glycobiology        ISSN： 0959-6658            Impact factor:   4.313


  22 in total

1.  Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants.

Authors:  T A Pitcovsky; J Mucci; P Alvarez; M S Leguizamón; O Burrone; P M Alzari; O Campetella
Journal:  Infect Immun       Date:  2001-03       Impact factor: 3.441

2.  Continuous nonradioactive method for screening trypanosomal trans-sialidase activity and its inhibitors.

Authors:  Paula A Sartor; Rosalía Agusti; Maria S Leguizamón; Oscar Campetella; Rosa M de Lederkremer
Journal:  Glycobiology       Date:  2010-04-07       Impact factor: 4.313

3.  Acylation-dependent export of Trypanosoma cruzi phosphoinositide-specific phospholipase C to the outer surface of amastigotes.

Authors:  Vicente de Paulo Martins; Michael Okura; Danijela Maric; David M Engman; Mauricio Vieira; Roberto Docampo; Silvia N J Moreno
Journal:  J Biol Chem       Date:  2010-07-20       Impact factor: 5.157

4.  The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents.

Authors:  María Virginia Tribulatti; Juan Mucci; Nico Van Rooijen; María Susana Leguizamón; Oscar Campetella
Journal:  Infect Immun       Date:  2005-01       Impact factor: 3.441

5.  Galactosyl-lactose sialylation using Trypanosoma cruzi trans-sialidase as the biocatalyst and bovine κ-casein-derived glycomacropeptide as the donor substrate.

Authors:  Maarten H Wilbrink; Geert A ten Kate; Sander S van Leeuwen; Peter Sanders; Erik Sallomons; Johannes A Hage; Lubbert Dijkhuizen; Johannis P Kamerling
Journal:  Appl Environ Microbiol       Date:  2014-07-25       Impact factor: 4.792

6.  Characterization and Diagnostic Application of Trypanosoma cruzi Trypomastigote Excreted-Secreted Antigens Shed in Extracellular Vesicles Released from Infected Mammalian Cells.

Authors:  Norma L Bautista-López; Momar Ndao; Fabio Vasquez Camargo; Takeshi Nara; Takeshi Annoura; Darryl B Hardie; Christoph H Borchers; Armando Jardim
Journal:  J Clin Microbiol       Date:  2016-12-14       Impact factor: 5.948

7.  Trypanosoma cruzi-Derived Neurotrophic Factor: Role in Neural Repair and Neuroprotection.

Authors:  Marina V Chuenkova; Mercio Pereiraperrin
Journal:  J Neuroparasitology       Date:  2010-07-26

8.  Inositolphosphoceramide metabolism in Trypanosoma cruzi as compared with other trypanosomatids.

Authors:  Rosa M De Lederkremer; Rosalía Agusti; Roberto Docampo
Journal:  J Eukaryot Microbiol       Date:  2011-02-21       Impact factor: 3.346

9.  Evidence for phospholipases from Trypanosoma cruzi active on phosphatidylinositol and inositolphosphoceramide.

Authors:  L E Bertello; M J Alves; W Colli; R M de Lederkremer
Journal:  Biochem J       Date:  2000-01-01       Impact factor: 3.857

10.  Formation and remodeling of inositolphosphoceramide during differentiation of Trypanosoma cruzi from trypomastigote to amastigote.

Authors:  Maria Laura Salto; Laura E Bertello; Mauricio Vieira; Roberto Docampo; Silvia N J Moreno; Rosa M de Lederkremer
Journal:  Eukaryot Cell       Date:  2003-08
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