Literature DB >> 9370933

A nitric oxide-releasing reagent, S-nitroso-N-acetylpenicillamine, enhances the expression of superoxide dismutases mRNA in the murine macrophage cell line RAW264-7.

H Sano1, M Hirai, H Saito, I Nakashima, K I Isobe.   

Abstract

Murine interferon-gamma (IFN-gamma) stimulates the murine macrophage tumour cell line RAW264-7 to produce nitric oxide (NO). IFN-gamma induces expression of inducible NO synthase (iNOS), manganese superoxide dismutase (Mn-SOD) and copper zinc SOD (CuZn-SOD) in these cells. To investigate the mechanism of induction of SOD expression, we added S-nitroso-N-acetyl penicillamine (SNAP) to RAW264-7 cells. SNAP enhanced the expression of Mn-SOD and CuZn-SOD. These results suggest that when producing NO, RAW264-7 cells express SOD that might protect them from NO toxicity.

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Year:  1997        PMID： 9370933      PMCID： PMC1363990          DOI： 10.1046/j.1365-2567.1997.00322.x

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  17 in total

1.  Cloning and characterization of inducible nitric oxide synthase from mouse macrophages.

Authors:  Q W Xie; H J Cho; J Calaycay; R A Mumford; K M Swiderek; T D Lee; A Ding; T Troso; C Nathan
Journal:  Science       Date:  1992-04-10       Impact factor: 47.728

2.  Feedback suppression of staphylococcal enterotoxin-stimulated T-lymphocyte proliferation by macrophages through inductive nitric oxide synthesis.

Authors:  K Isobe; I Nakashima
Journal:  Infect Immun       Date:  1992-11       Impact factor: 3.441

3.  Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase.

Authors:  D S Bredt; P M Hwang; C E Glatt; C Lowenstein; R R Reed; S H Snyder
Journal:  Nature       Date:  1991-06-27       Impact factor: 49.962

4.  Nitric oxide: a cytotoxic activated macrophage effector molecule.

Authors:  J B Hibbs; R R Taintor; Z Vavrin; E M Rachlin
Journal:  Biochem Biophys Res Commun       Date:  1988-11-30       Impact factor: 3.575

5.  Inhibition of nitrite formation from hydroxylammoniumchloride: a simple assay for superoxide dismutase.

Authors:  E F Elstner; A Heupel
Journal:  Anal Biochem       Date:  1976-02       Impact factor: 3.365

6.  Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

Authors:  J S Beckman; T W Beckman; J Chen; P A Marshall; B A Freeman
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

7.  Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

Authors:  A H Ding; C F Nathan; D J Stuehr
Journal:  J Immunol       Date:  1988-10-01       Impact factor: 5.422

8.  Extracellular superoxide dismutase, nitric oxide, and central nervous system O2 toxicity.

Authors:  T D Oury; Y S Ho; C A Piantadosi; J D Crapo
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

9.  Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells.

Authors:  C M Troy; M L Shelanski
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-05       Impact factor: 11.205

10.  Tumor necrosis factor-alpha increases Mn-SOD expression: protection against oxidant injury.

Authors:  B B Warner; M S Burhans; J C Clark; J R Wispé
Journal:  Am J Physiol       Date:  1991-04
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  2 in total

1.  Overexpression of CuZn superoxide dismutase protects RAW 264.7 macrophages against nitric oxide cytotoxicity.

Authors:  F Brockhaus; B Brüne
Journal:  Biochem J       Date:  1999-03-01       Impact factor: 3.857

2.  Antioxidative defense and mitochondrial thermogenic response in brown adipose tissue.

Authors:  Vesna Petrović; Biljana Buzadžić; Aleksandra Korać; Bato Korać
Journal:  Genes Nutr       Date:  2009-12-13       Impact factor: 5.523
  2 in total

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