BACKGROUND: Alcohol use is associated with breast cancer in many epidemiological studies. Most, however, have measured risk from recent consumption patterns, and only a few include analyses for duration of drinking or age that a woman started to drink. The authors studied the effect of these variables, as well as of recent alcohol consumption patterns, on breast cancer risk. METHODS: Data from a large case-control study conducted in Long Island, New York from 1 January 1984 to 31 December 1986 were used. A total of 1214 women aged 20-79 years with incident breast cancer were interviewed. A control was selected for each case from driver's license files, and matched on age and county of residence. Alcohol consumption was measured as: ever versus never, grams of alcohol per day, age started drinking, and total years drinking. RESULTS: After adjustment for breast cancer risk factors, the odds ratio for ever versus never drinking was 1.40 (95% confidence interval [CI] 1.09-1.79); odds ratios for > 0-5 and > or = 5 grams of alcohol use per day, as compared to nondrinkers, were 1.29 (95% CI: 1.00-1.65) and 1.46 (95% CI: 1.13-1.89), respectively. Age when drinking began was not related to breast cancer risk, but the greater the total years of drinking, up to 40 years (odds ratio 1.48, 95% CI: 1.13-1.93), the greater the risk. However, when grams per day and duration of drinking were simultaneously included in the multivariate model, duration was not important as a risk factor. This suggests that intensity of drinking may be the important factor for breast cancer risk. After covariate adjustment, risk from alcohol intake did not differ between pre- and postmenopausal women.
BACKGROUND:Alcohol use is associated with breast cancer in many epidemiological studies. Most, however, have measured risk from recent consumption patterns, and only a few include analyses for duration of drinking or age that a woman started to drink. The authors studied the effect of these variables, as well as of recent alcohol consumption patterns, on breast cancer risk. METHODS: Data from a large case-control study conducted in Long Island, New York from 1 January 1984 to 31 December 1986 were used. A total of 1214 women aged 20-79 years with incident breast cancer were interviewed. A control was selected for each case from driver's license files, and matched on age and county of residence. Alcohol consumption was measured as: ever versus never, grams of alcohol per day, age started drinking, and total years drinking. RESULTS: After adjustment for breast cancer risk factors, the odds ratio for ever versus never drinking was 1.40 (95% confidence interval [CI] 1.09-1.79); odds ratios for > 0-5 and > or = 5 grams of alcohol use per day, as compared to nondrinkers, were 1.29 (95% CI: 1.00-1.65) and 1.46 (95% CI: 1.13-1.89), respectively. Age when drinking began was not related to breast cancer risk, but the greater the total years of drinking, up to 40 years (odds ratio 1.48, 95% CI: 1.13-1.93), the greater the risk. However, when grams per day and duration of drinking were simultaneously included in the multivariate model, duration was not important as a risk factor. This suggests that intensity of drinking may be the important factor for breast cancer risk. After covariate adjustment, risk from alcohol intake did not differ between pre- and postmenopausal women.
Authors: Martha L Slattery; Abbie Lundgreen; Esther M John; Gabriela Torres-Mejia; Lisa Hines; Anna R Giuliano; Kathy B Baumgartner; Mariana C Stern; Roger K Wolff Journal: Nutr Cancer Date: 2015-01-28 Impact factor: 2.900
Authors: Heidi D Nelson; Bernadette Zakher; Amy Cantor; Rongwei Fu; Jessica Griffin; Ellen S O'Meara; Diana S M Buist; Karla Kerlikowske; Nicolien T van Ravesteyn; Amy Trentham-Dietz; Jeanne S Mandelblatt; Diana L Miglioretti Journal: Ann Intern Med Date: 2012-05-01 Impact factor: 25.391
Authors: Lindsay A Williams; Andrew F Olshan; Chui Kit Tse; Mary Elizabeth Bell; Melissa A Troester Journal: Cancer Causes Control Date: 2015-12-24 Impact factor: 2.506
Authors: N Hamajima; K Hirose; K Tajima; T Rohan; E E Calle; C W Heath; R J Coates; J M Liff; R Talamini; N Chantarakul; S Koetsawang; D Rachawat; A Morabia; L Schuman; W Stewart; M Szklo; C Bain; F Schofield; V Siskind; P Band; A J Coldman; R P Gallagher; T G Hislop; P Yang; L M Kolonel; A M Y Nomura; J Hu; K C Johnson; Y Mao; S De Sanjosé; N Lee; P Marchbanks; H W Ory; H B Peterson; H G Wilson; P A Wingo; K Ebeling; D Kunde; P Nishan; J L Hopper; G Colditz; V Gajalanski; N Martin; T Pardthaisong; S Silpisornkosol; C Theetranont; B Boosiri; S Chutivongse; P Jimakorn; P Virutamasen; C Wongsrichanalai; M Ewertz; H O Adami; L Bergkvist; C Magnusson; I Persson; J Chang-Claude; C Paul; D C G Skegg; G F S Spears; P Boyle; T Evstifeeva; J R Daling; W B Hutchinson; K Malone; E A Noonan; J L Stanford; D B Thomas; N S Weiss; E White; N Andrieu; A Brêmond; F Clavel; B Gairard; J Lansac; L Piana; R Renaud; A Izquierdo; P Viladiu; H R Cuevas; P Ontiveros; A Palet; S B Salazar; N Aristizabel; A Cuadros; L Tryggvadottir; H Tulinius; A Bachelot; M G Lê; J Peto; S Franceschi; F Lubin; B Modan; E Ron; Y Wax; G D Friedman; R A Hiatt; F Levi; T Bishop; K Kosmelj; M Primic-Zakelj; B Ravnihar; J Stare; W L Beeson; G Fraser; R D Bullbrook; J Cuzick; S W Duffy; I S Fentiman; J L Hayward; D Y Wang; A J McMichael; K McPherson; R L Hanson; M C Leske; M C Mahoney; P C Nasca; A O Varma; A L Weinstein; T R Moller; H Olsson; J Ranstam; R A Goldbohm; P A van den Brandt; R A Apelo; J Baens; J R de la Cruz; B Javier; L B Lacaya; C A Ngelangel; C La Vecchia; E Negri; E Marubini; M Ferraroni; M Gerber; S Richardson; C Segala; D Gatei; P Kenya; A Kungu; J G Mati; L A Brinton; R Hoover; C Schairer; R Spirtas; H P Lee; M A Rookus; F E van Leeuwen; J A Schoenberg; M McCredie; M D Gammon; E A Clarke; L Jones; A Neil; M Vessey; D Yeates; P Appleby; E Banks; V Beral; D Bull; B Crossley; A Goodill; J Green; C Hermon; T Key; N Langston; C Lewis; G Reeves; R Collins; R Doll; R Peto; K Mabuchi; D Preston; P Hannaford; C Kay; L Rosero-Bixby; Y T Gao; F Jin; J-M Yuan; H Y Wei; T Yun; C Zhiheng; G Berry; J Cooper Booth; T Jelihovsky; R MacLennan; R Shearman; Q-S Wang; C-J Baines; A B Miller; C Wall; E Lund; H Stalsberg; X O Shu; W Zheng; K Katsouyanni; A Trichopoulou; D Trichopoulos; A Dabancens; L Martinez; R Molina; O Salas; F E Alexander; K Anderson; A R Folsom; B S Hulka; L Bernstein; S Enger; R W Haile; A Paganini-Hill; M C Pike; R K Ross; G Ursin; M C Yu; M P Longnecker; P Newcomb; L Bergkvist; A Kalache; T M M Farley; S Holck; O Meirik Journal: Br J Cancer Date: 2002-11-18 Impact factor: 7.640
Authors: Margaret Wrensch; Terri Chew; Georgianna Farren; Janice Barlow; Flavia Belli; Christina Clarke; Christine A Erdmann; Marion Lee; Michelle Moghadassi; Roni Peskin-Mentzer; Charles P Quesenberry; Virginia Souders-Mason; Linda Spence; Marisa Suzuki; Mary Gould Journal: Breast Cancer Res Date: 2003-04-29 Impact factor: 6.466