Literature DB >> 9360602

Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein.

J Liu, P A Lynch, C Y Chien, G T Montelione, R M Krug, H M Berman.   

Abstract

The nonstructural protein (NS1 protein) of the influenza A virus binds to several types of RNAs. X-ray crystallographic analysis of the RNA-binding domain reveals a unique topology for the monomer as well as a novel six-helix structure for the dimer.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9360602     DOI： 10.1038/nsb1197-896

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN： 1072-8368


  65 in total

1.  A recurrent RNA-binding domain is appended to eukaryotic aminoacyl-tRNA synthetases.

Authors:  B Cahuzac; E Berthonneau; N Birlirakis; E Guittet; M Mirande
Journal:  EMBO J       Date:  2000-02-01       Impact factor: 11.598

2.  E4orf6 variants with separate abilities to augment adenovirus replication and direct nuclear localization of the E1B 55-kilodalton protein.

Authors:  Joseph S Orlando; David A Ornelles
Journal:  J Virol       Date:  2002-02       Impact factor: 5.103

3.  Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon.

Authors:  X Wang; M Li; H Zheng; T Muster; P Palese; A A Beg; A García-Sastre
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

4.  A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice.

Authors:  Nicola R Donelan; Christopher F Basler; Adolfo García-Sastre
Journal:  J Virol       Date:  2003-12       Impact factor: 5.103

5.  Refinement of homology-based protein structures by molecular dynamics simulation techniques.

Authors:  Hao Fan; Alan E Mark
Journal:  Protein Sci       Date:  2004-01       Impact factor: 6.725

6.  The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.

Authors:  Andreas Lingel; Bernd Simon; Elisa Izaurralde; Michael Sattler
Journal:  EMBO Rep       Date:  2005-12       Impact factor: 8.807

7.  Genetic analysis of influenza virus NS1 gene: a temperature-sensitive mutant shows defective formation of virus particles.

Authors:  Urtzi Garaigorta; Ana M Falcón; Juan Ortín
Journal:  J Virol       Date:  2005-12       Impact factor: 5.103

Review 8.  Antiviral silencing in animals.

Authors:  Hong-Wei Li; Shou-Wei Ding
Journal:  FEBS Lett       Date:  2005-08-31       Impact factor: 4.124

9.  (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus.

Authors:  James M Aramini; Keith Hamilton; Li-Chung Ma; G V T Swapna; Paul G Leonard; John E Ladbury; Robert M Krug; Gaetano T Montelione
Journal:  Structure       Date:  2014-02-27       Impact factor: 5.006

10.  Influenza A Virus Protein NS1 Exhibits Strain-Independent Conformational Plasticity.

Authors:  Sayantan Mitra; Dilip Kumar; Liya Hu; Banumathi Sankaran; Mahdi Muhammad Moosa; Andrew P Rice; Josephine C Ferreon; Allan Chris M Ferreon; B V Venkataram Prasad
Journal:  J Virol       Date:  2019-10-15       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.