Literature DB >> 9360601

A novel RNA-binding motif in influenza A virus non-structural protein 1.

C Y Chien, R Tejero, Y Huang, D E Zimmerman, C B Ríos, R M Krug, G T Montelione.   

Abstract

The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold. Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2' forms a novel arginine-rich nucleic acid binding motif.

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Year:  1997        PMID: 9360601     DOI: 10.1038/nsb1197-891

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN: 1072-8368


  60 in total

1.  A recurrent RNA-binding domain is appended to eukaryotic aminoacyl-tRNA synthetases.

Authors:  B Cahuzac; E Berthonneau; N Birlirakis; E Guittet; M Mirande
Journal:  EMBO J       Date:  2000-02-01       Impact factor: 11.598

2.  Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I.

Authors:  Alexander S Jureka; Alex B Kleinpeter; Gabriel Cornilescu; Claudia C Cornilescu; Chad M Petit
Journal:  Structure       Date:  2015-09-10       Impact factor: 5.006

3.  The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.

Authors:  Andreas Lingel; Bernd Simon; Elisa Izaurralde; Michael Sattler
Journal:  EMBO Rep       Date:  2005-12       Impact factor: 8.807

Review 4.  Antiviral silencing in animals.

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Journal:  FEBS Lett       Date:  2005-08-31       Impact factor: 4.124

Review 5.  Structural domains in RNAi.

Authors:  Robert E Collins; Xiaodong Cheng
Journal:  FEBS Lett       Date:  2005-08-09       Impact factor: 4.124

Review 6.  Virus counterdefense: diverse strategies for evading the RNA-silencing immunity.

Authors:  Feng Li; Shou-Wei Ding
Journal:  Annu Rev Microbiol       Date:  2006       Impact factor: 15.500

7.  The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway.

Authors:  Ji-Young Min; Robert M Krug
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-20       Impact factor: 11.205

8.  What can we learn by computing 13Calpha chemical shifts for X-ray protein models?

Authors:  Yelena A Arnautova; Jorge A Vila; Osvaldo A Martin; Harold A Scheraga
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2009-06-20

9.  (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus.

Authors:  James M Aramini; Keith Hamilton; Li-Chung Ma; G V T Swapna; Paul G Leonard; John E Ladbury; Robert M Krug; Gaetano T Montelione
Journal:  Structure       Date:  2014-02-27       Impact factor: 5.006

10.  Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells.

Authors:  E Hatada; S Saito; R Fukuda
Journal:  J Virol       Date:  1999-03       Impact factor: 5.103

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