Literature DB >> 9360588

Seizures, ventricular tachycardia, and rhabdomyolysis as a result of ingestion of venlafaxine and lamotrigine.

C Peano1, J B Leikin, P K Hanashiro.   

Abstract

Few cases of overdoses have been described involving venlafaxine, lamotrigine, or a combination of the two agents. We describe a combined venlafaxine and lamotrigine ingestion in a patient presenting with a seizure, ventricular tachycardia, and rhabdomyolysis. We conclude that patients with overdoses that involve venlafaxine can exhibit severe cardiac effects in addition to seizures, especially if venlafaxine is combined with other agents.

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Year:  1997        PMID: 9360588     DOI: 10.1016/s0196-0644(97)70093-3

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN: 0196-0644            Impact factor:   5.721


  5 in total

Review 1.  The QT interval and psychotropic medications in children: recommendations for clinicians.

Authors:  Paul McNally; Fiona McNicholas; Paul Oslizlok
Journal:  Eur Child Adolesc Psychiatry       Date:  2006-08-29       Impact factor: 4.785

2.  A fatal case of venlafaxine overdose.

Authors:  George M Bosse; Henry A Spiller; Aaron M Collins
Journal:  J Med Toxicol       Date:  2008-03

Review 3.  Venlafaxine extended-release: a review of its use in the management of major depression.

Authors:  K Wellington; C M Perry
Journal:  CNS Drugs       Date:  2001       Impact factor: 5.749

Review 4.  Cardiovascular toxicity due to venlafaxine poisoning in adults: a review of 235 consecutive cases.

Authors:  C Howell; A D Wilson; W S Waring
Journal:  Br J Clin Pharmacol       Date:  2007-02-12       Impact factor: 4.335

5.  Electrocardiogram changes and arrhythmias in venlafaxine overdose.

Authors:  Geoffrey K Isbister
Journal:  Br J Clin Pharmacol       Date:  2009-02-02       Impact factor: 4.335

  5 in total

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