Literature DB >> 9357139

Th1-type immunity is incompatible with successful pregnancy.

R Raghupathy1.   

Abstract

Several years ago, the rather provocative question was raised: is successful pregnancy a T helper 2 (Th2) phenomenon? Implicit in this argument is the corollary that unsuccessful pregnancy is a Th1-type situation. Here, evidence from murine and human pregnancy is presented to show that, since Th1-type cytokines mediate pregnancy loss, a shift towards Th1-type immunity may help resolve 'unexplained' pregnancy failure.

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Year:  1997        PMID： 9357139     DOI： 10.1016/s0167-5699(97)01127-4

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  156 in total

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10.  Acute Trypanosoma cruzi infection in mouse induces infertility or placental parasite invasion and ischemic necrosis associated with massive fetal loss.

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