Literature DB >> 9345912

Experimental assessment of the detection limit of genomic amplification by comparative genomic hybridization CGH.

F Parente1, P Gaudray, G F Carle, C Turc-Carel.   

Abstract

Artificial amplicons of known size, constructed by use of YACs featuring human 8p12 and 12q13, were analyzed by comparative genomic hybridization (CGH). A minimum of 15 Mb of overrepresented DNA sequences could be detected. The sensitivity is (1) not dependent on the chromosome site and (2) related to the size of the amplicon, decreasing with decreasing size.

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Year:  1997        PMID： 9345912     DOI： 10.1159/000134632

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  4 in total

1.  High-resolution mapping of genomic imbalance and identification of gene expression profiles associated with differential chemotherapy response in serous epithelial ovarian cancer.

Authors:  Marcus Bernardini; Chung-Hae Lee; Ben Beheshti; Mona Prasad; Monique Albert; Paula Marrano; Heather Begley; Patricia Shaw; Al Covens; Joan Murphy; Barry Rosen; Salomon Minkin; Jeremy A Squire; Pascale F Macgregor
Journal:  Neoplasia       Date:  2005-06       Impact factor: 5.715

2.  Genes proximal and distal to MYCN are highly expressed in human neuroblastoma as visualized by comparative expressed sequence hybridization.

Authors:  Cornelia Stock; Eva Bozsaky; Franz Watzinger; Ulrike Poetschger; Lukas Orel; Thomas Lion; Agata Kowalska; Peter F Ambros
Journal:  Am J Pathol       Date:  2007-12-28       Impact factor: 4.307

Review 3.  Advanced molecular cytogenetics in human and mouse.

Authors:  Kathleen Dorritie; Cristina Montagna; Michael J Difilippantonio; Thomas Ried
Journal:  Expert Rev Mol Diagn       Date:  2004-09       Impact factor: 5.225

4.  Chromosomal localization of DNA amplifications in neuroblastoma tumors using cDNA microarray comparative genomic hybridization.

Authors:  Ben Beheshti; Ilan Braude; Paula Marrano; Paul Thorner; Maria Zielenska; Jeremy A Squire
Journal:  Neoplasia       Date:  2003 Jan-Feb       Impact factor: 5.715
  4 in total

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