Literature DB >> 9339490

Dioxin is a promoter blocker, a promoter, and a net anticarcinogen.

G Kayajanian.   

Abstract

An ad hoc panel of dioxin experts convened by EPA's Science Advisory Board found the Agency's claim of cancer causation by dioxin unacceptable. This paper uses the very same two studies [Fingerhut (NIOSH) and Kociba] EPA relied upon to test the observations made in an unused third study [Bertazzi] to conclude that dioxin is (1) a promoter blocker of certain cancers, including all the cancers Agency scientists claimed dioxin promoted; (2) a promoter of some other cancers that EPA scientists failed to identify; and (3) a net anticarcinogen. Three independent total tumor reductions provide evidence of both cancer prevention and quantifiable risk reductions tied to specific dioxin levels. The author indirectly suggests a general cancer prevention treatment, even for cancers already initiated.

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Year:  1997        PMID: 9339490     DOI: 10.1006/rtph.1997.1129

Source DB:  PubMed          Journal:  Regul Toxicol Pharmacol        ISSN: 0273-2300            Impact factor:   3.271


  2 in total

Review 1.  Antagonistic combinations of occupational carcinogens.

Authors:  Hugo W Ruediger
Journal:  Int Arch Occup Environ Health       Date:  2005-10-14       Impact factor: 3.015

2.  Clinical trials of TCDD.

Authors:  Gary Kayajanian
Journal:  Nonlinearity Biol Toxicol Med       Date:  2003-04
  2 in total

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