A E Hurtt1, M O Smith. 1. Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523, USA.
Abstract
OBJECTIVE: To examine the effects that iatrogenic blood contamination would have on total protein concentration and nucleated cell count in CSF from clinically normal dogs and dogs with neurologic disease. DESIGN: Case-control study. STUDY POPULATION: 53 dogs confirmed to have neurologic disease and 21 clinically normal dogs. PROCEDURE: CSF samples were obtained from the cerebellomedullary cistern or the lumbar portion of the subarachnoid space. Red blood and nucleated cell counts were determined, and protein concentration was measured. RESULTS: RBC count was not significantly correlated with nucleated cell count or protein concentration in clinically normal dogs or dogs with neurologic disease. CLINICAL IMPLICATIONS: High CSF nucleated cell counts and protein concentrations are indicative of neurologic disease, even if samples contain moderate amounts of blood contamination.
OBJECTIVE: To examine the effects that iatrogenic blood contamination would have on total protein concentration and nucleated cell count in CSF from clinically normal dogs and dogs with neurologic disease. DESIGN: Case-control study. STUDY POPULATION: 53 dogs confirmed to have neurologic disease and 21 clinically normal dogs. PROCEDURE: CSF samples were obtained from the cerebellomedullary cistern or the lumbar portion of the subarachnoid space. Red blood and nucleated cell counts were determined, and protein concentration was measured. RESULTS: RBC count was not significantly correlated with nucleated cell count or protein concentration in clinically normal dogs or dogs with neurologic disease. CLINICAL IMPLICATIONS: High CSF nucleated cell counts and protein concentrations are indicative of neurologic disease, even if samples contain moderate amounts of blood contamination.
Authors: Tanja Alexandra Steinberg; Irene Christine Boettcher; Kaspar Matiasek; Katrin Hirschvogel; Katrin Hartmann; Anne Kunz; Anne Kuntz; Andrea Fischer Journal: Vet Clin Pathol Date: 2008-06 Impact factor: 1.180
Authors: Maria Puerto-Parada; Juan Carlos Arango-Sabogal; Marie-Ève Bilodeau; Christian Bédard; David Francoz; André Desrochers; Sylvain Nichols; Gilles Fecteau Journal: J Vet Intern Med Date: 2022-07-30 Impact factor: 3.175
Authors: Christopher L Mariani; Carolyn J Nye; Debra A Tokarz; Lauren Green; Jeanie Lau; Natalia Zidan; Peter J Early; Julien Guevar; Karen R Muñana; Natasha J Olby; Sarita Miles Journal: J Vet Intern Med Date: 2019-09-24 Impact factor: 3.333