Literature DB >> 9333064

Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica.

S Ankri1, T Miron, A Rabinkov, M Wilchek, D Mirelman.   

Abstract

The ability of Entamoeba histolytica trophozoites to destroy monolayers of baby hamster kidney cells is inhibited by allicin, one of the active principles of garlic. Cysteine proteinases, an important contributor to amebic virulence, as well as alcohol dehydrogenase, are strongly inhibited by allicin.

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Year:  1997        PMID： 9333064      PMCID： PMC164109     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

1.  Enzyme inhibition by allicin, the active principle of garlic.

Authors:  E D WILLS
Journal:  Biochem J       Date:  1956-07       Impact factor: 3.857

2.  Entamoeba histolytica and Entamoeba dispar: differences in numbers and expression of cysteine proteinase genes.

Authors:  I Bruchhaus; T Jacobs; M Leippe; E Tannich
Journal:  Mol Microbiol       Date:  1996-10       Impact factor: 3.501

3.  A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba.

Authors:  L S Diamond; D R Harlow; C C Cunnick
Journal:  Trans R Soc Trop Med Hyg       Date:  1978       Impact factor: 2.184

4.  Cysteine endopeptidases of Entamoeba histolytica.

Authors:  H Scholze; E Tannich
Journal:  Methods Enzymol       Date:  1994       Impact factor: 1.600

5.  Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

Authors:  T Mosmann
Journal:  J Immunol Methods       Date:  1983-12-16       Impact factor: 2.303

6.  The medical uses of garlic--fact and fiction.

Authors:  S Bolton; G Null; W M Troetel
Journal:  Am Pharm       Date:  1982-08

7.  Inhibition of growth of Entamoeba histolytica by allicin, the active principle of garlic extract (Allium sativum).

Authors:  D Mirelman; D Monheit; S Varon
Journal:  J Infect Dis       Date:  1987-07       Impact factor: 5.226

8.  Cloning of a virulence factor of Entamoeba histolytica. Pathogenic strains possess a unique cysteine proteinase gene.

Authors:  S Reed; J Bouvier; A S Pollack; J C Engel; M Brown; K Hirata; X Que; A Eakin; P Hagblom; F Gillin
Journal:  J Clin Invest       Date:  1993-04       Impact factor: 14.808

9.  Entamoeba histolytica: increase of enterotoxicity and of 53- and 75-kDa cysteine proteinases in a clone of higher virulence.

Authors:  F Navarro-García; L Chávez-Dueñas; V Tsutsumi; F Posadas del Río; R López-Revilla
Journal:  Exp Parasitol       Date:  1995-05       Impact factor: 2.011

10.  The major neutral proteinase of Entamoeba histolytica.

Authors:  W E Keene; M G Petitt; S Allen; J H McKerrow
Journal:  J Exp Med       Date:  1986-03-01       Impact factor: 14.307
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  22 in total

1.  N-thiolated beta-lactams: Studies on the mode of action and identification of a primary cellular target in Staphylococcus aureus.

Authors:  Kevin D Revell; Bart Heldreth; Timothy E Long; Seyoung Jang; Edward Turos
Journal:  Bioorg Med Chem       Date:  2006-12-20       Impact factor: 3.641

2.  Inhibitory effect of allicin on the growth of Babesia and Theileria equi parasites.

Authors:  Akram Ahmed Salama; Mahmoud AbouLaila; Mohamad Alaa Terkawi; Ahmed Mousa; Ahmed El-Sify; Mahmoud Allaam; Ahmed Zaghawa; Naoaki Yokoyama; Ikuo Igarashi
Journal:  Parasitol Res       Date:  2013-10-31       Impact factor: 2.289

3.  Immunomodulatory properties of borage (Echium amoenum) on BALB/c mice infected with Leishmania major.

Authors:  Nahid Hosseini; Mohsen Abolhassani
Journal:  J Clin Immunol       Date:  2011-01-12       Impact factor: 8.317

4.  Antimalarial activity of allicin, a biologically active compound from garlic cloves.

Authors:  Alida Coppi; Melissa Cabinian; David Mirelman; Photini Sinnis
Journal:  Antimicrob Agents Chemother       Date:  2006-05       Impact factor: 5.191

5.  Immunomodulatory and antiparasitic effects of garlic extract on Eimeria vermiformis-infected mice.

Authors:  Atef Mohammed Khalil; Masahiro Yasuda; Ayman Samir Farid; Mohamed Ibrahim Desouky; Mouchira Mohammed Mohi-Eldin; Mohie Haridy; Yoichiro Horii
Journal:  Parasitol Res       Date:  2015-04-18       Impact factor: 2.289

Review 6.  Antileishmanial and Immunomodulatory Activity of Allium sativum (Garlic): A Review.

Authors:  Masoud Foroutan-Rad; Khosrow Hazrati Tappeh; Shahram Khademvatan
Journal:  J Evid Based Complementary Altern Med       Date:  2015-12-30

7.  The antitrichomonal efficacy of garlic and metronidazole against Trichomonas gallinae infecting domestic pigeons.

Authors:  Sh A Seddiek; Mohamed M El-Shorbagy; Hanem F Khater; Ali M Ali
Journal:  Parasitol Res       Date:  2014-02-02       Impact factor: 2.289

8.  Comparison of in vitro activity of metronidazole and garlic-based product (Tomex®) on Trichomonas vaginalis.

Authors:  Ayman Nabil Ibrahim
Journal:  Parasitol Res       Date:  2013-03-02       Impact factor: 2.289

9.  Therapy of murine pulmonary aspergillosis with antibody-alliinase conjugates and alliin.

Authors:  Elena Appel; Alexandra Vallon-Eberhard; Aharon Rabinkov; Ori Brenner; Irina Shin; Keren Sasson; Yona Shadkchan; Nir Osherov; Steffen Jung; David Mirelman
Journal:  Antimicrob Agents Chemother       Date:  2009-11-30       Impact factor: 5.191

10.  Unsymmetric aryl-alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracis.

Authors:  Edward Turos; Kevin D Revell; Praveen Ramaraju; Danielle A Gergeres; Kerriann Greenhalgh; Ashley Young; Nalini Sathyanarayan; Sonja Dickey; Daniel Lim; Mamoun M Alhamadsheh; Kevin Reynolds
Journal:  Bioorg Med Chem       Date:  2008-05-17       Impact factor: 3.641
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