Literature DB >> 9330843

Poisoning by sodium channel blocking agents.

P F Kolecki1, S C Curry.   

Abstract

Poisoning by drugs that block voltage-gated sodium channels produces intraventricular conduction defects, myocardial depression, bradycardia, and ventricular arrhythmias. Human and animal reports suggest that hypertonic sodium bicarbonate may be effective therapy for numerous agents possessing sodium channel blocking properties, including cocaine, quinidine, procainamide, flecainide, mexiletine, bupivacaine, and others.

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Year:  1997        PMID： 9330843     DOI： 10.1016/s0749-0704(05)70371-7

Source DB:  PubMed          Journal:  Crit Care Clin        ISSN： 0749-0704            Impact factor:   3.598


  15 in total

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