Literature DB >> 931784

A new antifungal antibiotic, trichostatin.

N Tsuji, M Kobayashi, K Nagashima, Y Wakisaka, K Koizumi.   

Abstract

A new antibiotic, trichostatin, was isolated from the metabolites of strains of Streptomyces hygroscopicus. It is active against trichophytons and some fungi. The structure was determined to be a derivative of a primary hydroxamic acid by chemical and spectroscopic evidences.

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Year:  1976        PMID： 931784     DOI： 10.7164/antibiotics.29.1

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  66 in total

Review 1.  Discovery and mechanism of natural products as modulators of histone acetylation.

Authors:  Lilibeth A Salvador; Hendrik Luesch
Journal:  Curr Drug Targets       Date:  2012-07       Impact factor: 3.465

2.  Drug discovery from natural sources.

Authors:  Young-Won Chin; Marcy J Balunas; Hee Byung Chai; A Douglas Kinghorn
Journal:  AAPS J       Date:  2006-04-14       Impact factor: 4.009

3.  Age-related macular degeneration (AMD) mitochondria modulate epigenetic mechanisms in retinal pigment epithelial cells.

Authors:  Sonali Nashine; Anthony B Nesburn; Baruch D Kuppermann; M Cristina Kenney
Journal:  Exp Eye Res       Date:  2019-06-19       Impact factor: 3.467

Review 4.  Microbial natural products: molecular blueprints for antitumor drugs.

Authors:  Lesley-Ann Giddings; David J Newman
Journal:  J Ind Microbiol Biotechnol       Date:  2013-09-03       Impact factor: 3.346

Review 5.  An overview of naturally occurring histone deacetylase inhibitors.

Authors:  Bumki Kim; Jiyong Hong
Journal:  Curr Top Med Chem       Date:  2015       Impact factor: 3.295

Review 6.  Human telomerase inhibitors from microbial source.

Authors:  Kalarikkal Gopikrishnan Kiran; Muthusamy Palaniswamy; Jayaraman Angayarkanni
Journal:  World J Microbiol Biotechnol       Date:  2015-07-01       Impact factor: 3.312

7.  Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain.

Authors:  Young Jun Seo; Lisa Muench; Alicia Reid; Jinzhu Chen; Yeona Kang; Jacob M Hooker; Nora D Volkow; Joanna S Fowler; Sung Won Kim
Journal:  Bioorg Med Chem Lett       Date:  2013-10-30       Impact factor: 2.823

8.  Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector.

Authors:  Elvira Nieto-Pelegrin; Brendan Kenny; Narcisa Martinez-Quiles
Journal:  Cell Adh Migr       Date:  2014       Impact factor: 3.405

9.  Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists.

Authors:  David Mossman; Kyu-Tae Kim; Rodney J Scott
Journal:  BMC Cancer       Date:  2010-07-12       Impact factor: 4.430

10.  Preclinical studies of chemotherapy using histone deacetylase inhibitors in endometrial cancer.

Authors:  Noriyuki Takai; Hisashi Narahara
Journal:  Obstet Gynecol Int       Date:  2010-02-04
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