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Literature DB >> 9309178

Genetic interactions of Hox genes in limb development: learning from compound mutants.

Abstract

The recent generation of mice harboring multiple mutations in Hox genes has highlighted the role of these genes in controlling growth and patterning of the limb bud. The study of the phenotypes has not only revealed a complex network of genetic interactions among paralogous and non-paralogous Abdominal-B-related Hox genes but has also refined our understanding of their function.

Entities: Species

Mesh：

Year: 1997 PMID： 9309178 DOI： 10.1016/s0959-437x(97)80074-3

Source DB: PubMed Journal: Curr Opin Genet Dev ISSN： 0959-437X Impact factor: 5.578

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Cited

18 in total

1. 1,2,3 = 2,3,4: a solution to the problem of the homology of the digits in the avian hand.

Authors: G P Wagner; J A Gauthier
Journal: Proc Natl Acad Sci U S A Date: 1999-04-27 Impact factor: 11.205

Review 2. Molecular basis for skeletal variation: insights from developmental genetic studies in mice.

Authors: C Kappen; A Neubüser; R Balling; R Finnell
Journal: Birth Defects Res B Dev Reprod Toxicol Date: 2007-12

3. Rostral and caudal pharyngeal arches share a common neural crest ground pattern.

Authors: Maryline Minoux; Gregory S Antonarakis; Marie Kmita; Denis Duboule; Filippo M Rijli
Journal: Development Date: 2009-02 Impact factor: 6.868

4. A case of congenital bone marrow failure with radio-ulnar synostosis.

Authors: Hisao Yoshida; Yoshiko Hashii; Tokuko Okuda; Shigenori Kusuki; Emiko Sato; Akiko Inoue; Chihiro Kawakami; Miharu Yabe; Hideaki Ohta; Keiichi Ozono
Journal: Int J Hematol Date: 2010-01-22 Impact factor: 2.490

5. Deletions in HOXD13 segregate with an identical, novel foot malformation in two unrelated families.

Authors: F Goodman; M L Giovannucci-Uzielli; C Hall; W Reardon; R Winter; P Scambler
Journal: Am J Hum Genet Date: 1998-10 Impact factor: 11.025

6. Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications.

Authors: J Zákány; C Fromental-Ramain; X Warot; D Duboule
Journal: Proc Natl Acad Sci U S A Date: 1997-12-09 Impact factor: 11.205

Genetic interactions of Hox genes in limb development: learning from compound mutants.

1. 1,2,3 = 2,3,4: a solution to the problem of the homology of the digits in the avian hand.

Review 2. Molecular basis for skeletal variation: insights from developmental genetic studies in mice.

3. Rostral and caudal pharyngeal arches share a common neural crest ground pattern.

4. A case of congenital bone marrow failure with radio-ulnar synostosis.

5. Deletions in HOXD13 segregate with an identical, novel foot malformation in two unrelated families.

6. Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications.

7. Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis.

8. Missense mutations in the homeodomain of HOXD13 are associated with brachydactyly types D and E.

9. Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8.

10. Point mutation of Hoxd12 in mice.