Literature DB >> 9307865

The U1 snRNP complex: an autoantigen in connective tissue diseases. An update.

J M Klein Gunnewiek1, L B van de Putte, W J van Venrooij.   

Abstract

The U1 small nuclear ribonucleoprotein (snRNP) particle consists of an RNA backbone and eleven associated proteins. Both the RNA and some of the proteins are immunogenic in patients suffering from systemic lupus erythematosus or mixed connective tissue disease. An overview is given of the U1 snRNP particle with respect to its structure and function as well as its autoantigenicity.

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Year:  1997        PMID： 9307865

Source DB:  PubMed          Journal:  Clin Exp Rheumatol        ISSN： 0392-856X            Impact factor:   4.473


  14 in total

1.  Key residues revealed in a major conformational epitope of the U1-70K protein.

Authors:  E Welin Henriksson; M Wahren-Herlenius; I Lundberg; E Mellquist; I Pettersson
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-07       Impact factor: 11.205

2.  Autoantibody profiles in the sera of European patients with myositis.

Authors:  R Brouwer; G J Hengstman; W Vree Egberts; H Ehrfeld; B Bozic; A Ghirardello; G Grøndal; M Hietarinta; D Isenberg; J R Kalden; I Lundberg; H Moutsopoulos; P Roux-Lombard; J Vencovsky; A Wikman; H P Seelig; B G van Engelen ; W J van Venrooij
Journal:  Ann Rheum Dis       Date:  2001-02       Impact factor: 19.103

Review 3.  Autoantibodies and overlap syndromes in autoimmune rheumatic disease.

Authors:  E C Jury; D D'Cruz; W J Morrow
Journal:  J Clin Pathol       Date:  2001-05       Impact factor: 3.411

4.  RNA sequences that work as transcriptional activating regions.

Authors:  Shamol Saha; Aseem Z Ansari; Kevin A Jarrell; Mark Ptashne; Kevin A Jarell
Journal:  Nucleic Acids Res       Date:  2003-03-01       Impact factor: 16.971

5.  Characterization of an anti-RNA recombinant autoantibody fragment (scFv) isolated from a phage display library and detailed analysis of its binding site on U1 snRNA.

Authors:  S W Teunissen; M H Stassen; G J Pruijn; W J van Venrooij; R M Hoet
Journal:  RNA       Date:  1998-09       Impact factor: 4.942

6.  New Arabidopsis thaliana cytochrome c partners: a look into the elusive role of cytochrome c in programmed cell death in plants.

Authors:  Jonathan Martínez-Fábregas; Irene Díaz-Moreno; Katiuska González-Arzola; Simon Janocha; José A Navarro; Manuel Hervás; Rita Bernhardt; Antonio Díaz-Quintana; Miguel Á De la Rosa
Journal:  Mol Cell Proteomics       Date:  2013-09-09       Impact factor: 5.911

7.  Global and local dynamics of the human U1A protein determined by tryptophan fluorescence.

Authors:  J M Jean; C Clerte; K B Hall
Journal:  Protein Sci       Date:  1999-10       Impact factor: 6.725

8.  Human parvovirus B19 nonstructural protein NS1 enhanced the expression of cleavage of 70 kDa U1-snRNP autoantigen.

Authors:  Bor-Show Tzang; Der-Yuan Chen; Chun-Chou Tsai; Szu-Yi Chiang; Tsung-Ming Lin; Tsai-Ching Hsu
Journal:  J Biomed Sci       Date:  2010-05-25       Impact factor: 8.410

9.  The genotype of mice influences the autoimmune response to spliceosome proteins induced by cytomegalovirus gB immunization.

Authors:  J Lipes; E Skamene; M M Newkirk
Journal:  Clin Exp Immunol       Date:  2002-07       Impact factor: 4.330

Review 10.  The human exosome: an autoantigenic complex of exoribonucleases in myositis and scleroderma.

Authors:  R Brouwer; G J Pruijn; W J van Venrooij
Journal:  Arthritis Res       Date:  2000-12-20
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