Literature DB >> 9306936

Sputum cytology: a limited role.

A Gledhill1, C Bates, D Henderson, P DaCosta, G Thomas.   

Abstract

AIMS: To determine the cost and sensitivity of sputum cytology in routine use and to determine when sputum cytology is most appropriate.
METHODS: A retrospective study, based on all sputum cytology requests received in five histopathology/cytopathology laboratories in Yorkshire from 1 January to 31 December 1993. Cytology findings were correlated with histological diagnosis or clinical outcome, and related to the speciality of the referring clinician.
RESULTS: Laboratory practice and performance was similar in all five centres. The average laboratory cost of sputum cytology was 26.93. The mean absolute sensitivity was 36% and the specificity was 99.6%. The majority of specimens was submitted by general physicians or geriatricians. The largest proportion of positive specimens were submitted by chest physicians.
CONCLUSIONS: Often sputum cytology is used inappropriately as a screening investigation on, or soon after, admission. In addition, it is used inappropriately before bronchoscopy. Sputum cytology should be limited to individuals in whom a histological diagnosis is desired, but in whom bronchoscopy is inappropriate or unsuccessful.

Mesh:

Year:  1997        PMID: 9306936      PMCID: PMC500053          DOI: 10.1136/jcp.50.7.566

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  7 in total

1.  Changing utilization of cytopathology versus histopathology in the diagnosis of lung cancer.

Authors:  A E Fraire; J W McLarty; S D Greenberg
Journal:  Diagn Cytopathol       Date:  1991       Impact factor: 1.582

2.  Predictive value of sputum cytology.

Authors:  J Benbassat; A Regev; P E Slater
Journal:  Thorax       Date:  1987-03       Impact factor: 9.139

3.  Cytopathologic diagnosis of cancer in pulmonary material: a critical histopathologic correlation.

Authors:  Y S Erozan; J K Frost
Journal:  Acta Cytol       Date:  1970 Nov-Dec       Impact factor: 2.319

4.  Prospective study of combined use of bronchial aspirates and biopsy specimens in diagnosis and typing of centrally located lung tumours.

Authors:  E Piaton; M H Grillet-Ravigneaux; B Saugier; H Pellet
Journal:  BMJ       Date:  1995-03-11

5.  Diagnosis and typing of lung carcinomas by cytopathologic methods. A review of 108 cases.

Authors:  L D Truong; R D Underwood; S D Greenberg; J W McLarty
Journal:  Acta Cytol       Date:  1985 May-Jun       Impact factor: 2.319

6.  Ten years of respiratory cytopathology at Duke University Medical Center. I. The cytopathologic diagnosis of lung cancer during the years 1970 to 1974, noting the significance of specimen number and type.

Authors:  W W Johnston; E H Bossen
Journal:  Acta Cytol       Date:  1981 Mar-Apr       Impact factor: 2.319

7.  Cytologic and histologic correlation in primary lung cancer. A study of 154 cases with resectable tumors.

Authors:  T Tanaka; M Yamamoto; T Tamura; Y Moritani; M Miyai; S Hiraki; T Ohnoshi; I Kimura
Journal:  Acta Cytol       Date:  1985 Jan-Feb       Impact factor: 2.319

  7 in total
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Journal:  BMJ Open       Date:  2019-08-08       Impact factor: 2.692

2.  Neutral Desorption Extractive Electrospray Ionization Mass Spectrometry Analysis Sputum for Non-Invasive Lung Adenocarcinoma Detection.

Authors:  Qiaoling Zheng; Jianyong Zhang; Xinchen Wang; Wenxiong Zhang; Yipo Xiao; Sheng Hu; Jianjun Xu
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3.  Clinical features of bronchogenic large cell carcinoma confirmed by surgical resection.

Authors:  Moo Suk Park; Dong Hwan Shin; Kyung Young Chung; Jae Hee Cheong; Jae Ho Chung; Do Hoon Kim; Se Kyu Kim; Joon Chang; Joo Hang Kim; Sung Kyu Kim; Young Sam Kim
Journal:  Korean J Intern Med       Date:  2003-12       Impact factor: 2.884

  3 in total

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