O Uyama1, Y Yoshimoto, Y Yamamoto, A Kawai. 1. Division of Pathobiology, College of Nursing Art and Science, Akashi, Japan. uyama@kh.rim.or.jp
Abstract
BACKGROUND AND PURPOSE: Because of increased life expectancy, most postmenopausal women today suffer from osteoporosis and atherosclerotic diseases, which are currently considered unrelated diseases. Our study was aimed at analyzing relations between bone mineral density (BMD) and ultrasonographic assessment of carotid wall characteristics. METHODS: The relation of carotid atherosclerosis to BMD was examined in 30 postmenopausal women aged 67 to 85 years. High-resolution B-mode ultrasonography was performed, and the severity of carotid atherosclerosis was determined by plaque score. BMD was measured by dual-energy x-ray absorptiometry. RESULTS: The correlation of plaque score with low total BMD was r = .549 (P < .002). Multiple linear regression analysis indicated significant correlation of plaque score with total cholesterol level and low total BMD. CONCLUSIONS: Our results suggest a relation between carotid atherosclerosis, one of the major causes of ischemic cerebrovascular diseases, and osteoporosis.
BACKGROUND AND PURPOSE: Because of increased life expectancy, most postmenopausal women today suffer from osteoporosis and atherosclerotic diseases, which are currently considered unrelated diseases. Our study was aimed at analyzing relations between bone mineral density (BMD) and ultrasonographic assessment of carotid wall characteristics. METHODS: The relation of carotid atherosclerosis to BMD was examined in 30 postmenopausal women aged 67 to 85 years. High-resolution B-mode ultrasonography was performed, and the severity of carotid atherosclerosis was determined by plaque score. BMD was measured by dual-energy x-ray absorptiometry. RESULTS: The correlation of plaque score with low total BMD was r = .549 (P < .002). Multiple linear regression analysis indicated significant correlation of plaque score with total cholesterol level and low total BMD. CONCLUSIONS: Our results suggest a relation between carotid atherosclerosis, one of the major causes of ischemic cerebrovascular diseases, and osteoporosis.
Authors: P Pennisi; S S Signorelli; S Riccobene; G Celotta; L Di Pino; T La Malfa; C E Fiore Journal: Osteoporos Int Date: 2003-12-06 Impact factor: 4.507
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Authors: Ihsane Hmamouchi; Fadoua Allali; Hamza Khazzani; Loubna Bennani; Leila El Mansouri; Linda Ichchou; Mohammed Cherkaoui; Redouane Abouqal; Najia Hajjaj-Hassouni Journal: BMC Public Health Date: 2009-10-14 Impact factor: 3.295