Literature DB >> 9298015

Why "underpowered" trials are not necessarily unethical.

S J Edwards1, R J Lilford, D Braunholtz, J Jackson.   

Abstract

Keywords:  Biomedical and Behavioral Research; National Health Service

Mesh：

Year:  1997        PMID： 9298015     DOI： 10.1016/s0140-6736(97)02290-3

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


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  21 in total

Review 1.  Population newborn screening for inherited metabolic disease: current UK perspectives.

Authors:  A Green; R J Pollitt
Journal:  J Inherit Metab Dis       Date:  1999-06       Impact factor: 4.982

Review 2.  Rare diseases and the assessment of intervention: what sorts of clinical trials can we use?

Authors:  B Wilcken
Journal:  J Inherit Metab Dis       Date:  2001-04       Impact factor: 4.982

3.  Who's afraid of Thomas Bayes?

Authors:  R J Lilford; D Braunholtz
Journal:  J Epidemiol Community Health       Date:  2000-10       Impact factor: 3.710

4.  A cost consequence study of the impact of a dermatology-trained practice nurse on the quality of life of primary care patients with eczema and psoriasis.

Authors:  D Kernick; A Cox; R Powell; D Reinhold; J Sawkins; A Warin
Journal:  Br J Gen Pract       Date:  2000-07       Impact factor: 5.386

Review 5.  Strategy for randomised clinical trials in rare cancers.

Authors:  Say-Beng Tan; Keith B G Dear; Paolo Bruzzi; David Machin
Journal:  BMJ       Date:  2003-07-05

Review 6.  Current epistemological problems in evidence based medicine.

Authors:  R E Ashcroft
Journal:  J Med Ethics       Date:  2004-04       Impact factor: 2.903

Review 7.  Ethics, audit, and research: all shades of grey.

Authors:  Derick T Wade
Journal:  BMJ       Date:  2005-02-26

Review 8.  Essential statistical principles of clinical trials of pain treatments.

Authors:  Robert H Dworkin; Scott R Evans; Omar Mbowe; Michael P McDermott
Journal:  Pain Rep       Date:  2020-12-18

9.  Clinical research for rare disease: opportunities, challenges, and solutions.

Authors:  Robert C Griggs; Mark Batshaw; Mary Dunkle; Rashmi Gopal-Srivastava; Edward Kaye; Jeffrey Krischer; Tan Nguyen; Kathleen Paulus; Peter A Merkel
Journal:  Mol Genet Metab       Date:  2008-11-13       Impact factor: 4.797

Review 10.  Reporting of sample size calculation in randomised controlled trials: review.

Authors:  Pierre Charles; Bruno Giraudeau; Agnes Dechartres; Gabriel Baron; Philippe Ravaud
Journal:  BMJ       Date:  2009-05-12
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