Literature DB >> 9294018

Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

A D Cox1, C J Der.   

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Year:  1997        PMID: 9294018     DOI: 10.1016/s0304-419x(97)00011-5

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


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  53 in total

1.  In vitro and in vivo growth inhibition of human malignant astrocytoma cells by the farnesyltransferase inhibitor B1620.

Authors:  Masanori Kurimoto; Yutaka Hirashima; Hideo Hamada; Hironaga Kamiyama; Shoichi Nagai; Nakamasa Hayashi; Shunro Endo
Journal:  J Neurooncol       Date:  2003-01       Impact factor: 4.130

2.  RhoA biological activity is dependent on prenylation but independent of specific isoprenoid modification.

Authors:  Patricia A Solski; Whitney Helms; Patricia J Keely; Lishan Su; Channing J Der
Journal:  Cell Growth Differ       Date:  2002-08

3.  Investigation of the effect of the farnesyl protein transferase inhibitor R115777 on isoprenylation and intracellular signalling by the prostacyclin receptor.

Authors:  Sarah J O'Meara; B Therese Kinsella
Journal:  Br J Pharmacol       Date:  2004-08-31       Impact factor: 8.739

4.  The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis.

Authors:  K Jiang; D Coppola; N C Crespo; S V Nicosia; A D Hamilton; S M Sebti; J Q Cheng
Journal:  Mol Cell Biol       Date:  2000-01       Impact factor: 4.272

5.  Dexamethasone-induced decrease in HMG-CoA reductase and protein-farnesyl transferase activities does not impair ras processing in AR 4-2J cells.

Authors:  M Lambert; N D Bui
Journal:  Mol Cell Biochem       Date:  1999-12       Impact factor: 3.396

Review 6.  Unraveling the mechanism of the farnesyltransferase enzyme.

Authors:  Sérgio Filipe Sousa; Pedro Alexandrino Fernandes; Maria João Ramos
Journal:  J Biol Inorg Chem       Date:  2004-12-21       Impact factor: 3.358

7.  Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity.

Authors:  Thangaiah Subramanian; Suxia Liu; Jerry M Troutman; Douglas A Andres; H Peter Spielmann
Journal:  Chembiochem       Date:  2008-11-24       Impact factor: 3.164

8.  Ras Signaling in Breast Cancer.

Authors:  Aree Moon
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

9.  Identification of novel peptide substrates for protein farnesyltransferase reveals two substrate classes with distinct sequence selectivities.

Authors:  James L Hougland; Katherine A Hicks; Heather L Hartman; Rebekah A Kelly; Terry J Watt; Carol A Fierke
Journal:  J Mol Biol       Date:  2009-10-28       Impact factor: 5.469

10.  Farnesyltransferase inhibitors induce dramatic morphological changes of KNRK cells that are blocked by microtubule interfering agents.

Authors:  N Suzuki; K Del Villar; F Tamanoi
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-01       Impact factor: 11.205

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