Literature DB >> 9282118

A survey of telomerase activity in human cancer.

J W Shay1, S Bacchetti.   

Abstract

Research on the association of the ribonucleoprotein enzyme, telomerase, with human cancer has expanded rapidly in recent years. Essentially all major types of cancer have been screened and the presence of telomerase activity has been detected in the vast majority of cases. In this article we provide a summary, in table form, of the current data.

Entities:  

Mesh:

Substances:

Year:  1997        PMID: 9282118     DOI: 10.1016/S0959-8049(97)00062-2

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN: 0959-8049            Impact factor:   9.162


  737 in total

1.  Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA.

Authors:  H Niida; Y Shinkai; M P Hande; T Matsumoto; S Takehara; M Tachibana; M Oshimura; P M Lansdorp; Y Furuichi
Journal:  Mol Cell Biol       Date:  2000-06       Impact factor: 4.272

2.  Telomerase activity is sufficient to allow transformed cells to escape from crisis.

Authors:  T L Halvorsen; G Leibowitz; F Levine
Journal:  Mol Cell Biol       Date:  1999-03       Impact factor: 4.272

3.  A novel functional genomics approach identifies mTERT as a suppressor of fibroblast transformation.

Authors:  Q X Li; J M Robbins; P J Welch; F Wong-Staal; J R Barber
Journal:  Nucleic Acids Res       Date:  2000-07-01       Impact factor: 16.971

4.  Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.

Authors:  E Samper; J M Flores; M A Blasco
Journal:  EMBO Rep       Date:  2001-08-23       Impact factor: 8.807

5.  An alternative lifestyle for immortalized oral keratinocytes.

Authors:  R R Reddel
Journal:  J Clin Invest       Date:  2001-09       Impact factor: 14.808

Review 6.  Tiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology.

Authors:  J Fajkus; M Simícková; J Maláska
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2002-04-29       Impact factor: 6.237

7.  Rapid upregulation of telomerase activity in human leukemia HL-60 cells treated with clinical doses of the DNA-damaging drug etoposide.

Authors:  T J Moriarty; S Dupuis; C Autexier
Journal:  Leukemia       Date:  2002-06       Impact factor: 11.528

8.  Telomere length assessment in human archival tissues: combined telomere fluorescence in situ hybridization and immunostaining.

Authors:  Alan K Meeker; Wesley R Gage; Jessica L Hicks; Inpakala Simon; Jonathan R Coffman; Elizabeth A Platz; Gerrun E March; Angelo M De Marzo
Journal:  Am J Pathol       Date:  2002-04       Impact factor: 4.307

9.  Mapping of the gene for the human telomerase reverse transcriptase, hTERT, to chromosome 5p15.33 by fluorescence in situ hybridization.

Authors:  L A Bryce; N Morrison; S F Hoare; S Muir; W N Keith
Journal:  Neoplasia       Date:  2000 May-Jun       Impact factor: 5.715

10.  Expression of hTERT and hTR in cis reconstitutes and active human telomerase ribonucleoprotein.

Authors:  F Bachand; G Kukolj; C Autexier
Journal:  RNA       Date:  2000-05       Impact factor: 4.942

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.