Literature DB >> 9278500

A transgenic mouse strain expressing four drug-selectable marker genes.

K L Tucker1, Y Wang, J Dausman, R Jaenisch.   

Abstract

Murine embryonic stem (ES) cells are commonly cultured on feeder layers of primary murine embryonic fibroblasts (MEFs). Because gene targeting experiments often involve sequential selection for multiple-drug resistance in single ES cell lines, we have developed a new mouse strain which represents an economical donor for the production of multiple-drug resistant MEFs. MEFs prepared from the DR-4 mouse strain displayed resistance to concentrations of the drugs G418, 6-thioguanine, puromycin and hygromycin well above those used normally for the selection of drug-resistant ES cells.

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Year:  1997        PMID： 9278500      PMCID： PMC146932          DOI： 10.1093/nar/25.18.3745

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  13 in total

1.  Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells.

Authors:  K R Thomas; M R Capecchi
Journal:  Cell       Date:  1987-11-06       Impact factor: 41.582

2.  The mouse Pgk-1 gene promoter contains an upstream activator sequence.

Authors:  M W McBurney; L C Sutherland; C N Adra; B Leclair; M A Rudnicki; K Jardine
Journal:  Nucleic Acids Res       Date:  1991-10-25       Impact factor: 16.971

3.  Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells.

Authors:  S Thompson; A R Clarke; A M Pow; M L Hooper; D W Melton
Journal:  Cell       Date:  1989-01-27       Impact factor: 41.582

4.  Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice.

Authors:  E M Simpson; C C Linder; E E Sargent; M T Davisson; L E Mobraaten; J J Sharp
Journal:  Nat Genet       Date:  1997-05       Impact factor: 38.330

5.  Transgenic mice for the preparation of hygromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selections.

Authors:  K A Johnson; C P Lerner; L C Di Lacio; P W Laird; A H Sharpe; E M Simpson
Journal:  Nucleic Acids Res       Date:  1995-04-11       Impact factor: 16.971

6.  Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.

Authors:  K L Tucker; C Beard; J Dausmann; L Jackson-Grusby; P W Laird; H Lei; E Li; R Jaenisch
Journal:  Genes Dev       Date:  1996-04-15       Impact factor: 11.361

7.  Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells.

Authors:  H te Riele; E R Maandag; A Clarke; M Hooper; A Berns
Journal:  Nature       Date:  1990-12-13       Impact factor: 49.962

8.  HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells.

Authors:  M Hooper; K Hardy; A Handyside; S Hunter; M Monk
Journal:  Nature       Date:  1987 Mar 19-25       Impact factor: 49.962

9.  Inducible site-directed recombination in mouse embryonic stem cells.

Authors:  Y Zhang; C Riesterer; A M Ayrall; F Sablitzky; T D Littlewood; M Reth
Journal:  Nucleic Acids Res       Date:  1996-02-15       Impact factor: 16.971

10.  Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells.

Authors:  M Zijlstra; E Li; F Sajjadi; S Subramani; R Jaenisch
Journal:  Nature       Date:  1989-11-23       Impact factor: 49.962
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  39 in total

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2.  New positive/negative selectable markers for mammalian cells on the basis of Blasticidin deaminase-thymidine kinase fusions.

Authors:  C Karreman
Journal:  Nucleic Acids Res       Date:  1998-05-15       Impact factor: 16.971

3.  Gaucher Disease-Induced Pluripotent Stem Cells Display Decreased Erythroid Potential and Aberrant Myelopoiesis.

Authors:  Judi A Sgambato; Tea Soon Park; Diana Miller; Leelamma M Panicker; Ellen Sidransky; Yu Lun; Ola Awad; Søren M Bentzen; Elias T Zambidis; Ricardo A Feldman
Journal:  Stem Cells Transl Med       Date:  2015-06-10       Impact factor: 6.940

4.  Normal collagen and bone production by gene-targeted human osteogenesis imperfecta iPSCs.

Authors:  David R Deyle; Iram F Khan; Gaoying Ren; Pei-Rong Wang; Jordan Kho; Ulrike Schwarze; David W Russell
Journal:  Mol Ther       Date:  2011-10-25       Impact factor: 11.454

5.  Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange.

Authors:  Tim Pieters; Lieven Haenebalcke; Kenneth Bruneel; Niels Vandamme; Tino Hochepied; Jolanda van Hengel; Dagmar Wirth; Geert Berx; Jody J Haigh; Frans van Roy; Steven Goossens
Journal:  J Vis Exp       Date:  2017-04-27       Impact factor: 1.355

6.  Gaucher iPSC-derived macrophages produce elevated levels of inflammatory mediators and serve as a new platform for therapeutic development.

Authors:  Leelamma M Panicker; Diana Miller; Ola Awad; Vivek Bose; Yu Lun; Tea Soon Park; Elias T Zambidis; Judi A Sgambato; Ricardo A Feldman
Journal:  Stem Cells       Date:  2014-09       Impact factor: 6.277

7.  The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo.

Authors:  Alissa Minkovsky; Tahsin Stefan Barakat; Nadia Sellami; Mark Henry Chin; Nilhan Gunhanlar; Joost Gribnau; Kathrin Plath
Journal:  Cell Rep       Date:  2013-03-21       Impact factor: 9.423

8.  PKD1-Dependent Renal Cystogenesis in Human Induced Pluripotent Stem Cell-Derived Ureteric Bud/Collecting Duct Organoids.

Authors:  Shohei Kuraoka; Shunsuke Tanigawa; Atsuhiro Taguchi; Akitsu Hotta; Hitoshi Nakazato; Kenji Osafune; Akio Kobayashi; Ryuichi Nishinakamura
Journal:  J Am Soc Nephrol       Date:  2020-08-03       Impact factor: 10.121

9.  Mice deficient for the ets transcription factor elk-1 show normal immune responses and mildly impaired neuronal gene activation.

Authors:  Francesca Cesari; Stephan Brecht; Kristina Vintersten; Lam Giang Vuong; Matthias Hofmann; Karin Klingel; Jens-Jörg Schnorr; Sergei Arsenian; Hansjörg Schild; Thomas Herdegen; Franziska F Wiebel; Alfred Nordheim
Journal:  Mol Cell Biol       Date:  2004-01       Impact factor: 4.272

10.  Zinc-finger nuclease enhanced gene targeting in human embryonic stem cells.

Authors:  Brigham J Hartley; Stewart A Fabb; Ben A L Finnin; John M Haynes; Colin W Pouton
Journal:  J Vis Exp       Date:  2014-08-23       Impact factor: 1.355
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