Literature DB >> 9270298

Why do protein kinase cascades have more than one level?

G C Brown, J B Hoek, B N Kholodenko.   

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Year:  1997        PMID: 9270298     DOI: 10.1016/s0968-0004(97)82216-5

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


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  25 in total

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2.  Product dependence and bifunctionality compromise the ultrasensitivity of signal transduction cascades.

Authors:  Fernando Ortega; Luis Acerenza; Hans V Westerhoff; Francesc Mas; Marta Cascante
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3.  A combination of multisite phosphorylation and substrate sequestration produces switchlike responses.

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4.  Multisite protein phosphorylation makes a good threshold but can be a poor switch.

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5.  Mathematical models of specificity in cell signaling.

Authors:  Lee Bardwell; Xiufen Zou; Qing Nie; Natalia L Komarova
Journal:  Biophys J       Date:  2007-02-26       Impact factor: 4.033

6.  The potential for signal integration and processing in interacting MAP kinase cascades.

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7.  Biology using engineering tools: the negative feedback amplifier.

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8.  How MAP kinase modules function as robust, yet adaptable, circuits.

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9.  On sensitivity amplification in intracellular signaling cascades.

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10.  Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data.

Authors:  William W Chen; Birgit Schoeberl; Paul J Jasper; Mario Niepel; Ulrik B Nielsen; Douglas A Lauffenburger; Peter K Sorger
Journal:  Mol Syst Biol       Date:  2009-01-20       Impact factor: 11.429

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