Literature DB >> 21572255

Biology using engineering tools: the negative feedback amplifier.

Marc R Birtwistle1, Walter Kolch.   

Abstract

Negative feedback is an ubiquitous feature of biological networks. Recent work from Sturm and colleaguespresents experimental evidence that biological negative feedback can serve the same function as it does for engineered systems: robustness to perturbations within the feedback loop. Such behavior has important implications for how to attack deregulated signaling networks containing negative feedback in diseases such as cancer.

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Year:  2011        PMID： 21572255      PMCID： PMC3154361          DOI： 10.4161/cc.10.13.16245

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  73 in total

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Authors:  B A Keel; J S Davis
Journal:  Steroids       Date:  1999-09       Impact factor: 2.668

2.  Gene expression and specific binding of platelet-derived growth factor and its effect on DNA synthesis in human decidual cells.

Authors:  M Saji; M Taga; H Matsui; K Suyama; K Kurogi; H Minaguchi
Journal:  Mol Cell Endocrinol       Date:  1997-09-19       Impact factor: 4.102

Review 3.  The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions.

Authors:  Seunghee Yoon; Rony Seger
Journal:  Growth Factors       Date:  2006-03       Impact factor: 2.511

4.  Regulation of Raf-1 by direct feedback phosphorylation.

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Journal:  Mol Cell       Date:  2005-01-21       Impact factor: 17.970

Review 5.  Coordinating ERK/MAPK signalling through scaffolds and inhibitors.

Authors:  Walter Kolch
Journal:  Nat Rev Mol Cell Biol       Date:  2005-11       Impact factor: 94.444

Review 6.  Cell-signalling dynamics in time and space.

Authors:  Boris N Kholodenko
Journal:  Nat Rev Mol Cell Biol       Date:  2006-03       Impact factor: 94.444

Review 7.  Differential regulation and properties of MAPKs.

Authors:  M Raman; W Chen; M H Cobb
Journal:  Oncogene       Date:  2007-05-14       Impact factor: 9.867

8.  Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes.

Authors:  Aki Fujioka; Kenta Terai; Reina E Itoh; Kazuhiro Aoki; Takeshi Nakamura; Shinya Kuroda; Eisuke Nishida; Michiyuki Matsuda
Journal:  J Biol Chem       Date:  2006-01-17       Impact factor: 5.157

9.  Prediction and validation of the distinct dynamics of transient and sustained ERK activation.

Authors:  Satoru Sasagawa; Yu-ichi Ozaki; Kazuhiro Fujita; Shinya Kuroda
Journal:  Nat Cell Biol       Date:  2005-03-27       Impact factor: 28.824

10.  Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis.

Authors:  Suzanne Hagan; Fahd Al-Mulla; Elizabeth Mallon; Karin Oien; Rhona Ferrier; Barry Gusterson; Jorge J Curto García; Walter Kolch
Journal:  Clin Cancer Res       Date:  2005-10-15       Impact factor: 12.531
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  10 in total

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Journal:  Biophys J       Date:  2013-03-19       Impact factor: 4.033

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Journal:  Mol Biosyst       Date:  2014-07

3.  Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling.

Authors:  Michael Röring; Ricarda Herr; Gina J Fiala; Katharina Heilmann; Sandra Braun; Anja E Eisenhardt; Sebastian Halbach; David Capper; Andreas von Deimling; Wolfgang W Schamel; Darren N Saunders; Tilman Brummer
Journal:  EMBO J       Date:  2012-04-17       Impact factor: 11.598

4.  The secret life of kinases: functions beyond catalysis.

Authors:  Jens Rauch; Natalia Volinsky; David Romano; Walter Kolch
Journal:  Cell Commun Signal       Date:  2011-10-28       Impact factor: 5.712

5.  RMEL3, a novel BRAFV600E-associated long noncoding RNA, is required for MAPK and PI3K signaling in melanoma.

Authors:  Lucas Goedert; Cristiano G Pereira; Jason Roszik; Jessica R Plaça; Cibele Cardoso; Guo Chen; Wanleng Deng; Vashisht Gopal Yennu-Nanda; Wilson A Silva; Michael A Davies; Enilza M Espreafico
Journal:  Oncotarget       Date:  2016-06-14

6.  Correlated receptor transport processes buffer single-cell heterogeneity.

Authors:  Stefan M Kallenberger; Anne L Unger; Stefan Legewie; Konstantinos Lymperopoulos; Ursula Klingmüller; Roland Eils; Dirk-Peter Herten
Journal:  PLoS Comput Biol       Date:  2017-09-25       Impact factor: 4.475

7.  Temporal perturbation of ERK dynamics reveals network architecture of FGF2/MAPK signaling.

Authors:  Yannick Blum; Jan Mikelson; Maciej Dobrzyński; Hyunryul Ryu; Marc-Antoine Jacques; Noo Li Jeon; Mustafa Khammash; Olivier Pertz
Journal:  Mol Syst Biol       Date:  2019-11       Impact factor: 11.429

8.  Novel somatic mutations to PI3K pathway genes in metastatic melanoma.

Authors:  Austin Y Shull; Alicia Latham-Schwark; Poornema Ramasamy; Kristin Leskoske; Dora Oroian; Marc R Birtwistle; Phillip J Buckhaults
Journal:  PLoS One       Date:  2012-08-17       Impact factor: 3.240

9.  Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise.

Authors:  Marc R Birtwistle; Jens Rauch; Anatoly Kiyatkin; Edita Aksamitiene; Maciej Dobrzyński; Jan B Hoek; Walter Kolch; Babatunde A Ogunnaike; Boris N Kholodenko
Journal:  BMC Syst Biol       Date:  2012-08-24

10.  Multiple protein kinases influence the redistribution of fission yeast Clp1/Cdc14 phosphatase upon genotoxic stress.

Authors:  Matthew R Broadus; Kathleen L Gould
Journal:  Mol Biol Cell       Date:  2012-08-23       Impact factor: 4.138
  10 in total

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