A Mendivil1. 1. Ramón y Cajal Hospital, Department of Ophthalmology, Alcalá de Henares University, Madrid, Spain.
Abstract
PURPOSE: The author studied the effects of pupillary dilation on perimetry in a group of glaucomatous patients receiving timolol therapy. PATIENTS AND METHODS: A prospective study compared the visual fields of 23 patients with primary open-angle glaucoma of varying severity (mean defect: 3.84; short-term fluctuation: 1.91; pattern standard deviation [SD]: 3.61; corrected pattern SD: 3.12) before and after instillation of phenylephrine 10% using the Octopus 1-2-3 projection perimeter (INTERZEAG AG, Schlieren, Switzerland). RESULTS: The mean defect became impaired by an average of 3.01 (SD +/- 1.52) dB after administration of phenylephrine (p < 0.001). The pattern SD and the corrected pattern SD also became impaired with dilation by 1.51 dB (p < 0.01) and 1.73 dB (p < 0.05), respectively, after dilation. These changes varied across the visual field. The outer zone of the visual field had the greatest impairment after dilation with phenylephrine. CONCLUSIONS: Pupillary dilation in patients with glaucoma produces a nonuniform decrease in threshold sensitivities that is statistically greater on outer zone of the visual field.
PURPOSE: The author studied the effects of pupillary dilation on perimetry in a group of glaucomatouspatients receiving timolol therapy. PATIENTS AND METHODS: A prospective study compared the visual fields of 23 patients with primary open-angle glaucoma of varying severity (mean defect: 3.84; short-term fluctuation: 1.91; pattern standard deviation [SD]: 3.61; corrected pattern SD: 3.12) before and after instillation of phenylephrine 10% using the Octopus 1-2-3 projection perimeter (INTERZEAG AG, Schlieren, Switzerland). RESULTS: The mean defect became impaired by an average of 3.01 (SD +/- 1.52) dB after administration of phenylephrine (p < 0.001). The pattern SD and the corrected pattern SD also became impaired with dilation by 1.51 dB (p < 0.01) and 1.73 dB (p < 0.05), respectively, after dilation. These changes varied across the visual field. The outer zone of the visual field had the greatest impairment after dilation with phenylephrine. CONCLUSIONS: Pupillary dilation in patients with glaucoma produces a nonuniform decrease in threshold sensitivities that is statistically greater on outer zone of the visual field.
Authors: Sarwat Salim; Kevin Childers; Alvaro P C Lupinacci; George Z Hu; Vance Zemon; Peter A Netland Journal: Doc Ophthalmol Date: 2010-02-10 Impact factor: 2.379
Authors: Austin D Igelman; Cristy Ku; Sam Mershon; Mariana Matioli da Palma; J Jason McAnany; Robert A Hyde; Jason C Park; Paul Yang; Mark E Pennesi Journal: Transl Vis Sci Technol Date: 2021-12-01 Impact factor: 3.283