Literature DB >> 9259484

Estrogen differentially modulates nicotine-evoked dopamine release from the striatum of male and female rats.

D E Dluzen1, L I Anderson.   

Abstract

In the present experiment we examined the effects of an in vitro infusion of nicotine (10 microM) upon dopamine release from superfused striatum of castrated male and female rats treated or not treated with estrogen. Estrogen exerted bidirectional effects on nicotine-evoked dopamine release as a function of the sex of the animal. Nicotine-evoked dopamine release was increased in estrogen treated females and decreased in estrogen treated males. Peak nicotine-evoked dopamine output from estrogen treated females was significantly greater than that of estrogen treated males. These results may be related to the gender differences in response to nicotine and smoking behavior.

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Year:  1997        PMID: 9259484     DOI: 10.1016/s0304-3940(97)00487-4

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  31 in total

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Review 3.  Association of the DRD2 gene Taq1A polymorphism and smoking behavior: a meta-analysis and new data.

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4.  Variability in nicotine conditioned place preference and stress-induced reinstatement in mice: Effects of sex, initial chamber preference, and guanfacine.

Authors:  Angela M Lee; Cali A Calarco; Sherry A McKee; Yann S Mineur; Marina R Picciotto
Journal:  Genes Brain Behav       Date:  2019-08-13       Impact factor: 3.449

5.  Estradiol promotes the rewarding effects of nicotine in female rats.

Authors:  Rodolfo J Flores; Joseph A Pipkin; Kevin P Uribe; Adriana Perez; Laura E O'Dell
Journal:  Behav Brain Res       Date:  2016-04-06       Impact factor: 3.332

6.  In-utero exposure to maternal smoking is not linked to tobacco use in adulthood after controlling for genetic and family influences: a Swedish sibling study.

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Review 7.  Sex, ADHD symptoms, and smoking outcomes: an integrative model.

Authors:  Elizabeth E Van Voorhees; John T Mitchell; F Joseph McClernon; Jean C Beckham; Scott H Kollins
Journal:  Med Hypotheses       Date:  2012-02-15       Impact factor: 1.538

8.  Sex differences and the role of dopamine receptors in the reward-enhancing effects of nicotine and bupropion.

Authors:  Scott T Barrett; Trevor N Geary; Amy N Steiner; Rick A Bevins
Journal:  Psychopharmacology (Berl)       Date:  2016-10-01       Impact factor: 4.530

9.  Sex differences in time perception during smoking abstinence.

Authors:  Rebecca L Ashare; Joseph W Kable
Journal:  Nicotine Tob Res       Date:  2015-04       Impact factor: 4.244

10.  Female rats display dose-dependent differences to the rewarding and aversive effects of nicotine in an age-, hormone-, and sex-dependent manner.

Authors:  Oscar V Torres; Luis A Natividad; Hugo A Tejeda; Susan A Van Weelden; Laura E O'Dell
Journal:  Psychopharmacology (Berl)       Date:  2009-07-23       Impact factor: 4.530

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