Literature DB >> 9256059

Isolation of a cDNA encoding a widely expressed novel zinc finger protein with the LeR and KRAB-A domains.

M Yokoyama1, M Nakamura, K Okubo, K Matsubara, Y Nishi, T Matsumoto, A Fukushima.   

Abstract

We have isolated a human cDNA clone representing a novel human gene. The predicted 683-amino-acid protein, designated FPM315, contains nine C2H2-type zinc finger motifs and two regions homologous to the LeR domain, a finger-associated structural domain, and the A element of the Kruppel-associated box (KRAB) domain involved in transcriptional repression. The FPM315 mRNAs were expressed in all human tissues so far examined. A cross-species genomic hybridization indicates that the FPM315 gene is highly conserved among eukaryotes. These data suggest that FPM315 might play an important role in basic cellular processes.

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Year:  1997        PMID： 9256059     DOI： 10.1016/s0167-4781(97)00074-2

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  6 in total

1.  The zinc finger-associated SCAN box is a conserved oligomerization domain.

Authors:  A J Williams; S C Blacklow; T Collins
Journal:  Mol Cell Biol       Date:  1999-12       Impact factor: 4.272

2.  Cloning and characterization of a novel KRAB-domain-containing zinc finger gene (ZNF284L).

Authors:  Gang Yin; Chaoneng Ji; Li Zeng; Zebin Wang; Jiayan Wang; Zhouliang Shen; Tong Wu; Shaohua Gu; Yi Xie; Yumin Mao
Journal:  Mol Biol Rep       Date:  2006-06       Impact factor: 2.316

3.  Genomic targets of the KRAB and SCAN domain-containing zinc finger protein 263.

Authors:  Seth Frietze; Xun Lan; Victor X Jin; Peggy J Farnham
Journal:  J Biol Chem       Date:  2009-11-02       Impact factor: 5.157

4.  Molecular mapping of striatal subdivisions in juvenile Macaca Mulata.

Authors:  Joann O'Connor; Emil C Muly; Scott E Hemby
Journal:  Exp Neurol       Date:  2006-02-07       Impact factor: 5.330

5.  A Krüppel-associated box-zinc finger protein, NT2, represses cell-type-specific promoter activity of the alpha 2(XI) collagen gene.

Authors:  Kazuhiro Tanaka; Noriyuki Tsumaki; Christine A Kozak; Yoshihiro Matsumoto; Fumihiko Nakatani; Yukihide Iwamoto; Yoshihiko Yamada
Journal:  Mol Cell Biol       Date:  2002-06       Impact factor: 4.272

6.  Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3.

Authors:  M Centola; X Chen; R Sood; Z Deng; I Aksentijevich; T Blake; D O Ricke; X Chen; G Wood; N Zaks; N Richards; D Krizman; E Mansfield; S Apostolou; J Liu; N Shafran; A Vedula; M Hamon; A Cercek; T Kahan; D Gumucio; D F Callen; R I Richards; R K Moyzis; N A Doggett; F S Collins; P P Liu; N Fischel-Ghodsian; D L Kastner
Journal:  Genome Res       Date:  1998-11       Impact factor: 9.043
  6 in total

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