Literature DB >> 9241831

Synthesis and antimycobacterial activity of some new 3-heterocyclic substituted chromones.

R Gasparová1, M Lácová, H M el-Shaaer, Z Odlerová.   

Abstract

The aldol synthesis of benzimidazole, benzothiazole and benzothiazolium salt derivatives of chromones is described. The structures of the compounds have been proved by elemental analysis and 1H NMR spectra. The antimycobacterial activity of some of the prepared compounds have been tested in vitro against Mycobacterium tuberculosis (H37Rv) and Mycobacterium fortuitum (1021).

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Year:  1997        PMID: 9241831

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  5 in total

1.  Reactions of substituted furan-2-carboxaldehydes and furo[b]pyrrole type aldehydes with benzothiazolium salts.

Authors:  Zita Puterová; Alzbeta Krutosíková; Antonín Lycka; Tatiana Durceková
Journal:  Molecules       Date:  2004-03-31       Impact factor: 4.411

Review 2.  New small-molecule synthetic antimycobacterials.

Authors:  Lluis Ballell; Robert A Field; Ken Duncan; Robert J Young
Journal:  Antimicrob Agents Chemother       Date:  2005-06       Impact factor: 5.191

Review 3.  Benzotriazole: An overview on its versatile biological behavior.

Authors:  I Briguglio; S Piras; P Corona; E Gavini; M Nieddu; G Boatto; A Carta
Journal:  Eur J Med Chem       Date:  2014-09-30       Impact factor: 6.514

4.  3-Formylchromones IV. The rearrangement of 3-formylchromone enamines as a simple, facile route to novel pyrazolo[3,4-b]pyridines and the synthetic utility of the latter.

Authors:  Margita Lácová; Agnieszka Puchala; Eva Solcanyova; Jan Lac; Pavol Kois; Jarmila Chovancova; Danuta Rasala
Journal:  Molecules       Date:  2005-08-31       Impact factor: 4.411

5.  Reactions of 3-formylchromone with active methylene and methyl compounds and some subsequent reactions of the resulting condensation products.

Authors:  Renata Gasparová; Margita Lácová
Journal:  Molecules       Date:  2005-08-31       Impact factor: 4.411

  5 in total

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