Literature DB >> 9237449

In vivo imaging of fatty acid incorporation into brain to examine signal transduction and neuroplasticity involving phospholipids.

S I Rapoport1, D Purdon, H U Shetty, E Grange, Q Smith, C Jones, M C Chang.   

Abstract

An in vivo method is presented that allows quantification and imaging of fatty acid incorporation into different brain phospholipids in relation to membrane synthesis, neuroplasticity, and signal transduction. The method can be used with positron emission tomography, and may help to evaluate brain phospholipid metabolism in humans with brain tumors, neurodegenerative disease, cerebral ischemia or trauma, or neurotoxic effects of drugs or other agents.

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Year:  1997        PMID： 9237449     DOI： 10.1111/j.1749-6632.1997.tb46189.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  12 in total

1.  Functional brain imaging to identify affected subjects genetically at risk for Alzheimer's disease.

Authors:  S I Rapoport
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

2.  Dynamics of docosahexaenoic acid metabolism in the central nervous system: lack of effect of chronic lithium treatment.

Authors:  M C Chang; J M Bell; A D Purdon; E G Chikhale; E Grange
Journal:  Neurochem Res       Date:  1999-03       Impact factor: 3.996

3.  Maintaining brain health by monitoring inflammatory processes: a mechanism to promote successful aging.

Authors:  Caterina Rosano; Anna L Marsland; Peter J Gianaros
Journal:  Aging Dis       Date:  2011-09-30       Impact factor: 6.745

4.  Serum phospholipid docosahexaenonic acid is associated with cognitive functioning during middle adulthood.

Authors:  Matthew F Muldoon; Christopher M Ryan; Lei Sheu; Jeffrey K Yao; Sarah M Conklin; Stephen B Manuck
Journal:  J Nutr       Date:  2010-02-24       Impact factor: 4.798

Review 5.  In vivo fatty acid incorporation into brain phospholipids in relation to signal transduction and membrane remodeling.

Authors:  S I Rapoport
Journal:  Neurochem Res       Date:  1999-11       Impact factor: 3.996

6.  Intravenously injected [1-14C]arachidonic acid targets phospholipids, and [1-14C]palmitic acid targets neutral lipids in hearts of awake rats.

Authors:  E J Murphy; T A Rosenberger; C B Patrick; S I Rapoport
Journal:  Lipids       Date:  2000-08       Impact factor: 1.880

7.  Reduced palmitate turnover in brain phospholipids of pentobarbital-anesthetized rats.

Authors:  M A Contreras; M C Chang; D Kirkby; J M Bell; S I Rapoport
Journal:  Neurochem Res       Date:  1999-07       Impact factor: 3.996

8.  Omega-3 Supplementation and the Neural Correlates of Negative Affect and Impulsivity: A Double-Blind, Randomized, Placebo-Controlled Trial in Midlife Adults.

Authors:  Annie T Ginty; Matthew F Muldoon; Dora C H Kuan; Brittney Schirda; Thomas W Kamarck; J Richard Jennings; Stephen B Manuck; Peter J Gianaros
Journal:  Psychosom Med       Date:  2017-06       Impact factor: 4.312

Review 9.  A model for fatty acid transport into the brain.

Authors:  James A Hamilton; Kellen Brunaldi
Journal:  J Mol Neurosci       Date:  2007-09       Impact factor: 3.444

10.  Imaging incorporation of circulating docosahexaenoic acid into the human brain using positron emission tomography.

Authors:  John C Umhau; Weiyin Zhou; Richard E Carson; Stanley I Rapoport; Alla Polozova; James Demar; Nahed Hussein; Abesh K Bhattacharjee; Kaizong Ma; Giuseppe Esposito; Sharon Majchrzak; Peter Herscovitch; William C Eckelman; Karen A Kurdziel; Norman Salem
Journal:  J Lipid Res       Date:  2008-12-26       Impact factor: 5.922
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