Literature DB >> 921757

Partial purification of two lithocholic acid-binding proteins from rat liver 100 000g supernatants.

R C Strange, R Cramb, J D Hayes, I W Percy-Robb.   

Abstract

1. The partial purification of two lithocholic acid-binding proteins from liver 100 000g supernatants is described. 2. Gel-filtration, (NH4)2SO4 fractionation, Ca3(PO4)2 fractionation and ion-exchange chromatography were used. 3. Both proteins exhibited glutathione S-transferase activity; one may be the non-specific anion-binding protein ligandin. 4. Glutathione S-transferase activity of one of the binding proteins was inhibited by lithocholic acid.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 921757      PMCID： PMC1164923          DOI： 10.1042/bj1650425

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  12 in total

1.  Uptake of taurocholic acid into isolated rat-liver cells.

Authors:  L R Schwarz; R Burr; M Schwenk; E Pfaff; H Greim
Journal:  Eur J Biochem       Date:  1975-07-15

2.  Equilibrium-dialysis studies of the interaction between cholic acid and 100000g-supernatant preparations from the rat liver.

Authors:  R C Strange; I A Nimmo; I W Percy-Robb
Journal:  Biochem J       Date:  1976-05-15       Impact factor: 3.857

3.  The non-convalent binding of small molecules by ligandin. Interactions with steroids and their conjugates, fatty acids, bromosulphophthalein carcinogens, glutathione and realted compounds.

Authors:  E Tipping; B Ketterer; L Christodoulides; G Enderby
Journal:  Eur J Biochem       Date:  1976-08-16

4.  Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.

Authors:  W H Habig; M J Pabst; W B Jakoby
Journal:  J Biol Chem       Date:  1974-11-25       Impact factor: 5.157

5.  The identity of glutathione S-transferase B with ligandin, a major binding protein of liver.

Authors:  W H Habig; M J Pabst; G Fleischner; Z Gatmaitan; I M Arias; W B Jakoby
Journal:  Proc Natl Acad Sci U S A       Date:  1974-10       Impact factor: 11.205

6.  Ligandin: a hepatic protein which binds steroids, bilirubin, carcinogens and a number of exogenous organic anions.

Authors:  G Litwack; B Ketterer; I M Arias
Journal:  Nature       Date:  1971-12-24       Impact factor: 49.962

7.  Factors determining the maximal rate of organic anion secretion by the liver and further evidence on the hepatic site of action of the hormone secretin.

Authors:  E R O'Máille; T G Richards; A H Short
Journal:  J Physiol       Date:  1966-10       Impact factor: 5.182

8.  Binding of bile acids by 100 000g supernatants from rat liver.

Authors:  R C Strange; I A Nimmo; I W Percy-Robb
Journal:  Biochem J       Date:  1977-03-15       Impact factor: 3.857

9.  Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions.

Authors:  A J Levi; Z Gatmaitan; I M Arias
Journal:  J Clin Invest       Date:  1969-11       Impact factor: 14.808

10.  Role of hepatic anion-binding protein in bromsulphthalein conjugation.

Authors:  N Kaplowitz; I W Percy-Robb; N B Javitt
Journal:  J Exp Med       Date:  1973-08-01       Impact factor: 14.307
View more
  10 in total

1.  The initial-rate kinetics of mouse glutathione S-transferase YfYf. Evidence for an allosteric site for ethacrynic acid.

Authors:  M F Phillips; T J Mantle
Journal:  Biochem J       Date:  1991-05-01       Impact factor: 3.857

2.  Studies of the relationship between the catalytic activity and binding of non-substrate ligands by the glutathione S-transferases.

Authors:  T D Boyer; D A Vessey; C Holcomb; N Saley
Journal:  Biochem J       Date:  1984-01-01       Impact factor: 3.857

3.  A comparison of erythrocyte glutathione S-transferase activity from human foetuses and adults.

Authors:  R C Strange; J D Johnston; D R Coghill; R Hume
Journal:  Biochem J       Date:  1980-05-15       Impact factor: 3.857

4.  Cholic acid binding by glutathione S-transferases from rat liver cytosol.

Authors:  J D Hayes; R C Strange; I W Percy-Robb
Journal:  Biochem J       Date:  1980-01-01       Impact factor: 3.857

5.  The purification of the hepatic glutathione S-transferases of rainbow trout by glutathione affinity chromatography alters their isoelectric behaviour.

Authors:  P I Ramage; I A Nimmo
Journal:  Biochem J       Date:  1983-05-01       Impact factor: 3.857

6.  Bile acid inhibition of basic and neutral glutathione S-transferases in rat liver.

Authors:  J D Hayes; J Chalmers
Journal:  Biochem J       Date:  1983-12-01       Impact factor: 3.857

7.  Distribution of 3 alpha-hydroxysteroid dehydrogenase (bile acid binder) in rat small intestine: comparison with glutathione S-transferase subunits.

Authors:  W Yamamuro; A Stolz; H Takikawa; M Sugimoto; N Kaplowitz
Journal:  J Gastroenterol       Date:  1994-04       Impact factor: 7.527

8.  Inhibition of hepatic and extrahepatic glutathione S-transferases by primary and secondary bile acids.

Authors:  J D Hayes; T J Mantle
Journal:  Biochem J       Date:  1986-01-15       Impact factor: 3.857

9.  A study of the structures of the YaYa and YaYc glutathione S-transferases from rat liver cytosol. Evidence that the Ya monomer is responsible for lithocholate-binding activity.

Authors:  J D Hayes; R C Strange; I W Percy-Robb
Journal:  Biochem J       Date:  1981-08-01       Impact factor: 3.857

10.  Identification of two lithocholic acid-binding proteins. Separation of ligandin from glutathione S-transferase B.

Authors:  J D Hayes; R C Strange; I W Percy-Robb
Journal:  Biochem J       Date:  1979-09-01       Impact factor: 3.857
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.