| Literature DB >> 9216716 |
K Saitoh1, I Miura, A Ohshima, N Takahashi, M Kume, S Utsumi, Y Kobayashi, K Hashimoto, Y Hatano, T Nimura, M Saito, K Enomoto, M Ohhira, K Shimizu, M Ohki, A B Miura.
Abstract
The translocation t(8;21)(q22;q22) is found in 40% of cases of acute myeloid leukemia (AML) designated as the subtype M2 in the French-American-British (FAB) classification. The 8;21 translocation is clinically of interest because patients with this subtype have a good prognosis. We describe a masked type of the translocation, t(8;12;21)(q22.1;q24.1;q22.1). The translocation was first interpreted as t(8;12)(q22;q24) based on cytogenetics, but was reevaluated as a result of Southern blot and fluorescence in situ hybridization (FISH) analyses.Entities:
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Year: 1997 PMID： 9216716 DOI： 10.1016/s0165-4608(96)00320-2
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608