| Literature DB >> 921588 |
P Bösch, F Braun, J Eschberger, W Kovac, H P Spängler.
Abstract
The influence of a biological tissue glue--based on fibrinogen clotting--on bone healing has been investigated in animal experiments. Standardized cortical defects in the tibiae of rabbits were closed with a plug of homologous or heterologous fibrin. The course of restoration has been studied using histological techniques, x-ray examinations and isotopes (Ci 99 TC). Heterologous fibrin delays bone formation, due to a local immune response. Homologous fibrin on the other hand cubances and accelerates sprouting of capillary vessels and connective tissue cells which results in rapid new formation of bone.Entities:
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Year: 1977 PMID: 921588 DOI: 10.1007/bf00416954
Source DB: PubMed Journal: Arch Orthop Unfallchir ISSN: 0003-9330