Literature DB >> 9210695

Cross-resistance associated with development of resistance to isometamidium in a clone of Trypanosoma congolense.

A S Peregrine1, M A Gray, S K Moloo.   

Abstract

Resistance to isometamidium was increased 94-fold in a clone of Trypanosoma congolense (clone IL 1180) by repeated subcurative treatment of infected mice for 11 months. This was associated with 3.4-, 33-, and 4.2-fold increases in resistance to diminazene, homidium, and quinapyramine, respectively. Both T. congolense IL 1180 and the resistant derivative were able to undergo cyclical development in Glossina morsitans centralis tsetse flies, producing hypopharyngeal infection rates of 40.0 and 39.8%, respectively.

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Year:  1997        PMID： 9210695      PMCID： PMC163969     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  20 in total

1.  Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock of Trypanosoma congolense.

Authors:  A S Peregrine; G Knowles; A I Ibitayo; J R Scott; S K Moloo; N B Murphy
Journal:  Parasitology       Date:  1991-02       Impact factor: 3.234

Review 2.  The pharmacology of isometamidium.

Authors:  L D Kinabo; J A Bogan
Journal:  J Vet Pharmacol Ther       Date:  1988-09       Impact factor: 1.786

3.  Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia.

Authors:  W Mulugeta; J Wilkes; W Mulatu; P A Majiwa; R Masake; A S Peregrine
Journal:  Acta Trop       Date:  1997-04-15       Impact factor: 3.112

4.  Cryopreservation of pathogenic African trypanosomes in situ: metacyclic and bloodstream forms.

Authors:  F K Dar; G S Ligthart; A J Wilson
Journal:  J Protozool       Date:  1972-08

5.  An improved parasitological technique for the diagnosis of African trypanosomiasis.

Authors:  M Murray; P K Murray; W I McIntyre
Journal:  Trans R Soc Trop Med Hyg       Date:  1977       Impact factor: 2.184

6.  Resistance of cattle to tsetse-transmitted challenge with Trypanosoma brucei or Trypanosoma congolense after spontaneous recovery from syringe-passaged infections.

Authors:  V M Nantulya; A J Musoke; F R Rurangirwa; S K Moloo
Journal:  Infect Immun       Date:  1984-02       Impact factor: 3.441

Review 7.  Present status of chemotherapy and chemoprophylaxis of animal trypanosomiasis in the Eastern hemisphere.

Authors:  T M Leach; C J Roberts
Journal:  Pharmacol Ther       Date:  1981       Impact factor: 12.310

8.  Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs.

Authors:  T A Shapiro; P T Englund
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

9.  Interference between drug-resistant and drug-sensitive stocks of Trypanosoma congolense in goats.

Authors:  K R Sones; P H Holmes; G M Urquhart
Journal:  Res Vet Sci       Date:  1989-07       Impact factor: 2.534

10.  The sensitivity to trypanocidal drugs of Trypanosoma vivax isolated in Kenya and Somalia.

Authors:  A Schönefeld; D Röttcher; S K Moloo
Journal:  Trop Med Parasitol       Date:  1987-09
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  5 in total

1.  Comparative Sensitivity and Specificity of the 7SL sRNA Diagnostic Test for Animal Trypanosomiasis.

Authors:  Maria Contreras Garcia; Emily Walshe; Pieter C Steketee; Edith Paxton; Javier Lopez-Vidal; Michael C Pearce; Keith R Matthews; Fatima Ezzahra-Akki; Alec Evans; Karen Fairlie-Clark; Jacqueline B Matthews; Finn Grey; Liam J Morrison
Journal:  Front Vet Sci       Date:  2022-04-05

2.  Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacin.

Authors:  Vincent Delespaux; Hervé Sèna Vitouley; Tanguy Marcotty; Niko Speybroeck; Dirk Berkvens; Krisna Roy; Stanny Geerts; Peter Van den Bossche
Journal:  PLoS Negl Trop Dis       Date:  2010-09-28

Review 3.  The animal trypanosomiases and their chemotherapy: a review.

Authors:  Federica Giordani; Liam J Morrison; Tim G Rowan; Harry P DE Koning; Michael P Barrett
Journal:  Parasitology       Date:  2016-10-10       Impact factor: 3.234

Review 4.  An Update on African Trypanocide Pharmaceutics and Resistance.

Authors:  Keneth Iceland Kasozi; Ewan Thomas MacLeod; Ibrahim Ntulume; Susan Christina Welburn
Journal:  Front Vet Sci       Date:  2022-03-07

5.  Isometamidium chloride and homidium chloride fail to cure mice infected with Ethiopian Trypanosoma evansi type A and B.

Authors:  Gebrekrustos Mekonnen; Elmi Fahiye Mohammed; Weldu Kidane; Awol Nesibu; Hagos Yohannes; Nick Van Reet; Philippe Büscher; Hadush Birhanu
Journal:  PLoS Negl Trop Dis       Date:  2018-09-12
  5 in total

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