Literature DB >> 9202370

Serum levels of soluble form of Fas molecule in patients with congestive heart failure.

M Okuyama1, S Yamaguchi, N Nozaki, M Yamaoka, M Shirakabe, H Tomoike.   

Abstract

Compared with soluble Fas molecule (sFas, an inhibitor of Fas-mediated apoptosis) in normal volunteers, the serum level of sFas significantly increased by 41% in New York Heart Association (NYHA) class III (p <0.05) and by 97% in NYHA class IV patients with congestive heart failure (p <0.001). Furthermore, sFas showed correlations with soluble forms of TNF receptor-p55 (RI) and -p75 (RII) (r = 0.68 and r = 0.56) which inhibit activities of TNF alpha.

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Year:  1997        PMID： 9202370     DOI： 10.1016/s0002-9149(97)00228-2

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN： 0002-9149            Impact factor:   2.778


  11 in total

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