Literature DB >> 9196698

Genes and the development of vascular disease.

C A Foy1, P J Grant.   

Abstract

Clinical vascular disease occurs as the result of the chronic development of atherosclerosis, often with acute occlusive thrombus formation as the final event. Both atherosclerotic and thrombotic disorders are complex processes resulting from genetic and environmental interactions. We review genes currently implicated as risk factors and the approaches for identifying novel genetic risk factors.

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Year:  1997        PMID： 9196698      PMCID： PMC2431308          DOI： 10.1136/pgmj.73.859.271

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  28 in total

1.  Genetic variation at the plasminogen activator inhibitor-1 locus is associated with altered levels of plasma plasminogen activator inhibitor-1 activity.

Authors:  S Dawson; A Hamsten; B Wiman; A Henney; S Humphries
Journal:  Arterioscler Thromb       Date:  1991 Jan-Feb

2.  Gene therapy for cardiovascular disease.

Authors:  D W Muller
Journal:  Br Heart J       Date:  1994-10

3.  Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study.

Authors:  T W Meade; V Ruddock; Y Stirling; R Chakrabarti; G J Miller
Journal:  Lancet       Date:  1993-10-30       Impact factor: 79.321

4.  Polymorphisms of the angiotensin-converting-enzyme gene in subjects who die from coronary heart disease.

Authors:  A E Evans; O Poirier; F Kee; L Lecerf; E McCrum; T Falconer; J Crane; D F O'Rourke; F Cambien
Journal:  Q J Med       Date:  1994-04

5.  Deletion polymorphism in angiotensin-converting enzyme gene associated with parental history of myocardial infarction.

Authors:  L Tiret; F Kee; O Poirier; V Nicaud; L Lecerf; A Evans; J P Cambou; D Arveiler; G Luc; P Amouyel
Journal:  Lancet       Date:  1993-04-17       Impact factor: 79.321

6.  The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells.

Authors:  S J Dawson; B Wiman; A Hamsten; F Green; S Humphries; A M Henney
Journal:  J Biol Chem       Date:  1993-05-25       Impact factor: 5.157

7.  Determinants of plasminogen activator inhibitor 1 activity in treated NIDDM and its relation to a polymorphism in the plasminogen activator inhibitor 1 gene.

Authors:  A Panahloo; V Mohamed-Ali; A Lane; F Green; S E Humphries; J S Yudkin
Journal:  Diabetes       Date:  1995-01       Impact factor: 9.461

8.  Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

Authors:  R S Spielman; R E McGinnis; W J Ewens
Journal:  Am J Hum Genet       Date:  1993-03       Impact factor: 11.025

9.  Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

Authors:  L Tiret; B Rigat; S Visvikis; C Breda; P Corvol; F Cambien; F Soubrier
Journal:  Am J Hum Genet       Date:  1992-07       Impact factor: 11.025

10.  A genome-wide search for human type 1 diabetes susceptibility genes.

Authors:  J L Davies; Y Kawaguchi; S T Bennett; J B Copeman; H J Cordell; L E Pritchard; P W Reed; S C Gough; S C Jenkins; S M Palmer
Journal:  Nature       Date:  1994-09-08       Impact factor: 49.962
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  1 in total

1.  Gene/Environment interaction in atherosclerosis: an example of clinical medicine as seen from the evolutionary perspective.

Authors:  Gerhard Mertens
Journal:  Int J Hypertens       Date:  2010-03-25       Impact factor: 2.420
  1 in total

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