| Literature DB >> 9192019 |
N Feng1, M A Franco, H B Greenberg.
Abstract
The murine model of homologous rotavirus infection has been used to study the determinants of protection. The local IgA immune response appears to be the critical factor in generating protective immunity after natural infection. A series of knockout mice were used to evaluate the contribution of T cells and B cells to immunity and resolution from primary infection. Both arms of immune system played a role in the resolution of primary infection but antibody was much more important for prevention of reinfection.Entities:
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Year: 1997 PMID： 9192019 DOI： 10.1007/978-1-4899-1828-4_35
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622