Literature DB >> 9175710

Modulation of 6-hydroxydopamine oxidation by various proteins.

A Padiglia1, R Medda, A Lorrai, G Biggio, E Sanna, G Floris.   

Abstract

The spontaneous autoxidation of the neurotoxin 6-hydroxydopamine proceeds by a free radical chain reaction involving the superoxide anion radical and produces the corresponding chromogen 6-hydroxydopamine quinone and hydrogen peroxide. The rate of this reaction is increased in the presence of ceruloplasmin and peroxidase, and reduced by superoxide dismutase, catalase, and DT-diaphorase. We report some explanations of why these proteins may increase or reduce the rate of autoxidation of 6-hydroxydopamine.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9175710     DOI： 10.1016/s0006-2952(96)00716-2

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


  9 in total

1.  Alterations in the development of rat cerebellum and impaired behavior of juvenile rats after neonatal 6-OHDA treatment.

Authors:  I Djatchkova-Podkletnova; H Alho
Journal:  Neurochem Res       Date:  2005-12       Impact factor: 3.996

2.  Neurotoxin mechanisms and processes relevant to Parkinson's disease: an update.

Authors:  Juan Segura-Aguilar; Richard M Kostrzewa
Journal:  Neurotox Res       Date:  2015-01-29       Impact factor: 3.911

3.  Possible Effects of Copper and Ceruloplasmin Levels on Auditory Event Potentials in Boys with Attention Deficit Hyperactivity Disorder.

Authors:  Özgür Yorbik; Caner Mutlu; Mehmet Fatih Özdağ; Abdullah Olgun; Gül Eryilmaz; Semih Ayta
Journal:  Noro Psikiyatr Ars       Date:  2016-09-20       Impact factor: 1.339

Review 4.  Ceruloplasmin and what it might do.

Authors:  J Healy; K Tipton
Journal:  J Neural Transm (Vienna)       Date:  2007-04-04       Impact factor: 3.575

Review 5.  The 6-hydroxydopamine model of Parkinson's disease.

Authors:  Nicola Simola; Micaela Morelli; Anna R Carta
Journal:  Neurotox Res       Date:  2007-04       Impact factor: 3.911

6.  6-Hydroxydopamine: a far from simple neurotoxin.

Authors:  Damir Varešlija; Keith F Tipton; Gavin P Davey; Andrew G McDonald
Journal:  J Neural Transm (Vienna)       Date:  2020-01-01       Impact factor: 3.575

7.  Ceruloplasmin protects against rotenone-induced oxidative stress and neurotoxicity.

Authors:  Akiyo Hineno; Kazuma Kaneko; Kunihiro Yoshida; Shu-ichi Ikeda
Journal:  Neurochem Res       Date:  2011-06-26       Impact factor: 3.996

8.  Protective effect of tetrahydroxystilbene glucoside on 6-OHDA-induced apoptosis in PC12 cells through the ROS-NO pathway.

Authors:  Lizhen Tao; Xiaofeng Li; Lingling Zhang; Jiyu Tian; Xiaobing Li; Xin Sun; Xuefen Li; Lin Jiang; Xiaojun Zhang; Jianzong Chen
Journal:  PLoS One       Date:  2011-10-06       Impact factor: 3.240

9.  Thymol protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson's disease via inhibiting oxidative stress.

Authors:  Saeideh Nourmohammadi; Sanaz Yousefi; Mahboubeh Manouchehrabadi; Mona Farhadi; Zahra Azizi; Anahita Torkaman-Boutorabi
Journal:  BMC Complement Med Ther       Date:  2022-02-10
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.