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Literature DB >> 9174978

Antiviral activity of galangin isolated from the aerial parts of Helichrysum aureonitens.

J J Meyer¹, A J Afolayan, M B Taylor, D Erasmus.

Abstract

The in vitro antiviral activity of galangin (3,5,7-trihydroxyflavone), the major antimicrobial compound isolated from the shoots of Helichrysum aureonitens, was investigated against herpes simplex virus type 1 (HSV-1), coxsackie B virus type 1 (Cox B1), adenovirus type 31 (Ad31) and reovirus. At concentrations ranging from 12-47 micrograms/ml galangin showed significant antiviral activity against HSV-1 and CoxB1, limited activity against reovirus, and no antiviral activity against Ad31.

Entities: Chemical Species

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Year: 1997 PMID： 9174978 DOI： 10.1016/s0378-8741(97)01514-6

Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360

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Cited

17 in total

Review 1. Plant products as antimicrobial agents.

Authors: M M Cowan
Journal: Clin Microbiol Rev Date: 1999-10 Impact factor: 26.132

2. Antiviral effects of blackberry extract against herpes simplex virus type 1.

Authors: Robert J Danaher; Chunmei Wang; Jin Dai; Russell J Mumper; Craig S Miller
Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Date: 2011-09

3. Biologically active compounds of Helichrysum arenarium (L.) Moench.

Authors: E Czinner; A Kéry; K Hagymási; A Blázovics; A Lugasi; E Szöke; E Lemberkovics
Journal: Eur J Drug Metab Pharmacokinet Date: 1999 Oct-Dec Impact factor: 2.441

4. Galangin, a dietary flavonoid, improves antioxidant status and reduces hyperglycemia-mediated oxidative stress in streptozotocin-induced diabetic rats.

Authors: Amal A Aloud; Chinnadurai Veeramani; Chandramohan Govindasamy; Mohammed A Alsaif; Ahmed S El Newehy; Khalid S Al-Numair
Journal: Redox Rep Date: 2016-12-28 Impact factor: 4.412

10. Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia.

Authors: Chuanhong Wu; Jianxin Chen; Chang Chen; Wei Wang; Limei Wen; Kuo Gao; Xiuping Chen; Sihuai Xiong; Huihui Zhao; Shaojing Li
Journal: Sci Rep Date: 2015-11-05 Impact factor: 4.379

Antiviral activity of galangin isolated from the aerial parts of Helichrysum aureonitens.

Review 1. Plant products as antimicrobial agents.

2. Antiviral effects of blackberry extract against herpes simplex virus type 1.

3. Biologically active compounds of Helichrysum arenarium (L.) Moench.

4. Galangin, a dietary flavonoid, improves antioxidant status and reduces hyperglycemia-mediated oxidative stress in streptozotocin-induced diabetic rats.

5. Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets.

6. Galangin Suppresses Pro-Inflammatory Gene Expression in Polyinosinic-Polycytidylic Acid-Stimulated Microglial Cells.

Review 7. Antimicrobial activity of flavonoids.

8. Galangin, a natural flavonoid reduces mitochondrial oxidative damage in streptozotocin-induced diabetic rats.

9. Galangin (3,5,7-trihydroxyflavone) shields human keratinocytes from ultraviolet B-induced oxidative stress.

10. Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia.