Literature DB >> 917360

The failure of the cat to desaturate linoleic acid; its nutritional implications.

A G Hassam, J P Rivers, M A Crawford.   

Abstract

In vivo administration of 1-14C-linoleic acid to domestic cats demonstrated that these animals are unable to convert this essential fatty acid to its physiologically active metabolities. This experiment confirms the absence of both the delta6 and delta8 desaturases in the cat, and suggests that this species has a dietary requirement for polyunsaturated fatty acids of animal origin.

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Year:  1977        PMID: 917360     DOI: 10.1159/000176079

Source DB:  PubMed          Journal:  Nutr Metab        ISSN: 0029-6678            Impact factor:   4.169


  10 in total

1.  Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets.

Authors:  Luciano Trevizan; Alexandre de Mello Kessler; J Thomas Brenna; Peter Lawrence; Mark K Waldron; John E Bauer
Journal:  Lipids       Date:  2012-01-12       Impact factor: 1.880

2.  A vertebrate fatty acid desaturase with Delta 5 and Delta 6 activities.

Authors:  N Hastings; M Agaba; D R Tocher; M J Leaver; J R Dick; J R Sargent; A J Teale
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-27       Impact factor: 11.205

3.  Fatty acid metabolism in marine fish: low activity of fatty acyl delta5 desaturation in gilthead sea bream (Sparus aurata) cells.

Authors:  D R Tocher; C Ghioni
Journal:  Lipids       Date:  1999-05       Impact factor: 1.880

4.  Vertebrate fatty acyl desaturase with Δ4 activity.

Authors:  Yuanyou Li; Oscar Monroig; Liang Zhang; Shuqi Wang; Xiaozhong Zheng; James R Dick; Cuihong You; Douglas R Tocher
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-08       Impact factor: 11.205

5.  The desaturation and elongation of (14)C-labelled polyunsaturated fatty acids by pike (Esox lucius L.) in vivo.

Authors:  R J Henderson; M T Park; J R Sargent
Journal:  Fish Physiol Biochem       Date:  1995-06       Impact factor: 2.794

6.  Liver desaturase activities and FA composition in monkeys. Effect of a low-protein diet.

Authors:  María C Marín; Héctor M Pucciarelli; María J T de Alaniz
Journal:  Lipids       Date:  2003-05       Impact factor: 1.880

Review 7.  Vitamin E and selenium participation in fatty acid desaturation. A proposal for an enzymatic function of these nutrients.

Authors:  J P Infante
Journal:  Mol Cell Biochem       Date:  1986-02       Impact factor: 3.396

8.  Actions of prostaglandin precursors and other unsaturated fatty acids on conduction time and refractory period in the cat heart in situ.

Authors:  B L Bayer; W Förster
Journal:  Br J Pharmacol       Date:  1979-06       Impact factor: 8.739

9.  Metabolism of linoleic acid in the cat.

Authors:  A J Sinclair; J G McLean; E A Monger
Journal:  Lipids       Date:  1979-11       Impact factor: 1.880

Review 10.  Peculiarities of one-carbon metabolism in the strict carnivorous cat and the role in feline hepatic lipidosis.

Authors:  Adronie Verbrugghe; Marica Bakovic
Journal:  Nutrients       Date:  2013-07-19       Impact factor: 5.717

  10 in total

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