Literature DB >> 9159437

Intracytoplasmic sperm injection (ICSI) and chromosomally abnormal spermatozoa.

P A In't Veld1, F J Broekmans, H F de France, P L Pearson, M H Pieters, R J van Kooij.   

Abstract

An infertile couple was referred for intracytoplasmic sperm injection (ICSI) because of primary infertility and oligoasthenoteratozoospermia (OAT) in the male. It was observed that although the sperm cells presented with an unusual head size and multiple tails they were able to fertilize the oocytes after ICSI. Subsequent molecular cytogenetic analysis demonstrated de-novo chromosome abnormalities in virtually all sperm cells with 40% diploidy and 24% triploidy in addition to aneuploidy for the sex chromosomes.

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Year:  1997        PMID： 9159437     DOI： 10.1093/humrep/12.4.752

Source DB:  PubMed          Journal:  Hum Reprod        ISSN： 0268-1161            Impact factor:   6.918


  16 in total

1.  Chromosome 21 disomy in the spermatozoa of the fathers of children with trisomy 21, in a population with a high prevalence of Down syndrome: increased incidence in cases of paternal origin.

Authors:  J Blanco; E Gabau; D Gómez; N Baena; M Guitart; J Egozcue; F Vidal
Journal:  Am J Hum Genet       Date:  1998-10       Impact factor: 11.025

2.  A new AURKC mutation causing macrozoospermia: implications for human spermatogenesis and clinical diagnosis.

Authors:  Mariem Ben Khelifa; Raoudha Zouari; Radu Harbuz; Lazhar Halouani; Christophe Arnoult; Joël Lunardi; Pierre F Ray
Journal:  Mol Hum Reprod       Date:  2011-07-06       Impact factor: 4.025

3.  Sex chromosomal analysis of spermatozoa from infertile men using fluorescence in situ hybridization.

Authors:  N Nishikawa; I Murakami; K Ikuta; K Suzumori
Journal:  J Assist Reprod Genet       Date:  2000-02       Impact factor: 3.412

4.  Implications of sperm chromosome abnormalities in recurrent miscarriage.

Authors:  C Rubio; C Simón; J Blanco; F Vidal; Y Mínguez; J Egozcue; J Crespo; J Remohí; A Pellicer
Journal:  J Assist Reprod Genet       Date:  1999-05       Impact factor: 3.412

5.  Increased incidence of meiotic anomalies in oligoasthenozoospermic males preselected for intracytoplasmic sperm injection.

Authors:  S Egozcue; J M Vendrell; F Garcia; A Veiga; B Aran; P N Barri; J Egozcue
Journal:  J Assist Reprod Genet       Date:  2000-07       Impact factor: 3.412

Review 6.  Meiotic recombination and male infertility: from basic science to clinical reality?

Authors:  Michael C Hann; Patricio E Lau; Helen G Tempest
Journal:  Asian J Androl       Date:  2011-02-07       Impact factor: 3.285

7.  The effects of age and abnormal sperm count on the nondisjunction of spermatozoa.

Authors:  H Asada; K Sueoka; T Hashiba; M Kuroshima; N Kobayashi; Y Yoshimura
Journal:  J Assist Reprod Genet       Date:  2000-01       Impact factor: 3.412

Review 8.  Genetic aspects of monomorphic teratozoospermia: a review.

Authors:  Marc De Braekeleer; Minh Huong Nguyen; Frédéric Morel; Aurore Perrin
Journal:  J Assist Reprod Genet       Date:  2015-02-25       Impact factor: 3.412

9.  DNA fragmentation, mitochondrial dysfunction and chromosomal aneuploidy in the spermatozoa of oligoasthenoteratozoospermic males.

Authors:  Chung-Hsien Liu; Hui-Mei Tsao; Tzu-Chun Cheng; Hui-Mei Wu; Chun-Chia Huang; Chung-I Chen; David Pei-cheng Lin; Maw-Sheng Lee
Journal:  J Assist Reprod Genet       Date:  2004-04       Impact factor: 3.412

10.  Chromosome analysis of human spermatozoa with morphologically abnormal heads by injection into mouse oocytes.

Authors:  Seiji Watanabe
Journal:  Reprod Med Biol       Date:  2004-08-10
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