PURPOSE: To look for changes in the motor cortex in patients with brain tumors. METHODS: Both cerebral hemispheres in seven patients with brain tumors were examined with functional MR imaging during a motor task performed by the hand opposite the site of tumor. The ratio of the activated area in the motor cortex ipsilateral/contralateral to the tested hand was calculated for each subject. Twenty healthy subjects were also examined in the same manner for comparison. RESULTS: The ratio of the ipsilateral/contralateral activated area was abnormally high in three patients with tumor-related paresis of the tested hand. The ratio was significantly greater in patients with paresis than in healthy subjects. CONCLUSION: This study demonstrated increased activity in the ipsilateral (unaffected) motor area during a hand motor task in patients with brain tumor and paresis, which was thought to reflect compensatory reorganization induced by the functional damage.
PURPOSE: To look for changes in the motor cortex in patients with brain tumors. METHODS: Both cerebral hemispheres in seven patients with brain tumors were examined with functional MR imaging during a motor task performed by the hand opposite the site of tumor. The ratio of the activated area in the motor cortex ipsilateral/contralateral to the tested hand was calculated for each subject. Twenty healthy subjects were also examined in the same manner for comparison. RESULTS: The ratio of the ipsilateral/contralateral activated area was abnormally high in three patients with tumor-related paresis of the tested hand. The ratio was significantly greater in patients with paresis than in healthy subjects. CONCLUSION: This study demonstrated increased activity in the ipsilateral (unaffected) motor area during a hand motor task in patients with brain tumor and paresis, which was thought to reflect compensatory reorganization induced by the functional damage.
Authors: T Krings; M Schreckenberger; V Rohde; H Foltys; U Spetzger; O Sabri; M H Reinges; S Kemeny; P T Meyer; W Möller-Hartmann; M Korinth; J M Gilsbach; U Buell; A Thron Journal: J Neurol Neurosurg Psychiatry Date: 2001-12 Impact factor: 10.154
Authors: F E Roux; K Boulanouar; D Ibarrola; M Tremoulet; F Chollet; I Berry Journal: J Neurol Neurosurg Psychiatry Date: 2000-10 Impact factor: 10.154
Authors: John L Ulmer; Hendrikus G Krouwer; Wade M Mueller; M Sahin Ugurel; Mehmet Kocak; Leighton P Mark Journal: AJNR Am J Neuroradiol Date: 2003-02 Impact factor: 3.825
Authors: P T Meyer; L Sturz; O Sabri; M Schreckenberger; U Spetzger; K S Setani; H-J Kaiser; U Buell Journal: J Neurol Neurosurg Psychiatry Date: 2003-04 Impact factor: 10.154
Authors: Lakshminarayan Srinivasan; Wael F Asaad; Daniel T Ginat; John T Gale; Darin D Dougherty; Ziv M Williams; Terrence J Sejnowski; Emad N Eskandar Journal: PLoS One Date: 2013-02-27 Impact factor: 3.240