Literature DB >> 9155074

Dosimetric evaluation of compensation in radiotherapy of the breast: MLC intensity modulation and physical compensators.

V N Hansen1, P M Evans, G S Shentall, S J Helyer, J R Yarnold, W Swindell.   

Abstract

BACKGROUND AND
PURPOSE: Electronic portal images may be used to design the compensation required to maximise dose uniformity in the breast from opposed tangential beams.
MATERIALS AND METHODS: Four methods of implementing the desired compensation have been studied: a simple wedge, a physical compensator in conjunction with a wedge; one open field plus four shaped multi-leaf-collimated (MLC) fields, and one wedged field in conjunction with three shaped MLC fields. Evaluation was performed using thermoluminescent dosimeters (TLDs) placed inside a phantom which was designed to mimic the human breast. The measured results are compared with both the prediction of the in-house compensation design software and with the dose predicted by the GE Target II planning system. The implications of each method for the time taken to plan and deliver treatment were analysed.
RESULTS: The dose inhomogeneity, as measured at seven points in the central plane was greatest for the simple wedge (root mean square (rms) = 4.5%) compared to an open field plus four shaped MLC fields (rms = 2.2%), a wedged field plus three shaped MLC fields (rms = 3.3%), and the physical compensator (rms = 2.4%). The times required to plan and prepare these treatments varied considerably. The standard wedged treatment required under 15 min; both MLC-based and the physical compensator treatments required approximately 50 min. Differences of treatment delivery times were up to 8 min.
CONCLUSIONS: These results indicate that the dose inhomogeneity can be reduced by beam intensity modulation designed using EPIDs.

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Mesh:

Year:  1997        PMID: 9155074     DOI: 10.1016/s0167-8140(96)01895-6

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  3 in total

1.  Skin dose study of chest wall treatment with tomotherapy.

Authors:  Khosrow Javedan; Geoffrey Zhang; Richard Mueller; Eleanor Harris; Lawrence Berk; Kenneth Forster
Journal:  Jpn J Radiol       Date:  2009-11-27       Impact factor: 2.374

2.  Electronic tissue compensation achieved with both dynamic and static multileaf collimator in eclipse treatment planning system for Clinac 6 EX and 2100 CD Varian linear accelerators: Feasibility and dosimetric study.

Authors:  Rajesh A Kinhikar; Pramod K Sharma; Sachin Patkar; Chandrashekhar M Tambe; Deepak D Deshpande
Journal:  J Med Phys       Date:  2007-04

3.  Automatic Planning of Whole Breast Radiation Therapy Using Machine Learning Models.

Authors:  Yang Sheng; Taoran Li; Sua Yoo; Fang-Fang Yin; Rachel Blitzblau; Janet K Horton; Yaorong Ge; Q Jackie Wu
Journal:  Front Oncol       Date:  2019-08-07       Impact factor: 6.244

  3 in total

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