Literature DB >> 9151877

Efficient pseudotyping of murine leukemia virus particles with chimeric human foamy virus envelope proteins.

D Lindemann1, M Bock, M Schweizer, A Rethwilm.   

Abstract

Incorporation of human foamy virus (HFV) envelope proteins into murine leukemia virus (MuLV) particles was studied in a transient transfection packaging cell system. We report here that wild-type HFV envelope protein can pseudotype MuLV particles, albeit at low efficiency. Complete or partial removal of the HFV cytoplasmic tail resulted in an abolishment or reduction of HFV-mediated infectivity, implicating a role of the HFV envelope cytoplasmic tail in the pseudotyping of MuLV particles. Mutation of the endoplasmic reticulum retention signal present in the HFV envelope cytoplasmic tail did not result in a higher relative infectivity of pseudotyped retroviral vectors. However, a chimeric envelope protein, containing an unprocessed MuLV envelope cytoplasmic domain fused to a truncated HFV envelope protein, showed an enhanced HFV specific infectivity as a result of an increased incorporation of chimeric envelope proteins into MuLV particles.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9151877      PMCID： PMC191705     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  40 in total

1.  Reverse transcription. Foamy viruses bubble on.

Authors:  R A Weiss
Journal:  Nature       Date:  1996-03-21       Impact factor: 49.962

2.  Generation of packaging cell lines for pseudotyped retroviral vectors of the G protein of vesicular stomatitis virus by using a modified tetracycline inducible system.

Authors:  S T Chen; A Iida; L Guo; T Friedmann; J K Yee
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-17       Impact factor: 11.205

3.  A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes.

Authors:  D S Ory; B A Neugeboren; R C Mulligan
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-15       Impact factor: 11.205

4.  In vitro infection of primary and retrovirus-infected human leukocytes by human foamy virus.

Authors:  J A Mikovits; P M Hoffman; A Rethwilm; F W Ruscetti
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

5.  Expression of human foamy virus reverse transcriptase involves a spliced pol mRNA.

Authors:  I Jordan; J Enssle; E Güttler; B Mauer; A Rethwilm
Journal:  Virology       Date:  1996-10-01       Impact factor: 3.616

6.  Inducible, high-level production of infectious murine leukemia retroviral vector particles pseudotyped with vesicular stomatitis virus G envelope protein.

Authors:  Y Yang; E F Vanin; M A Whitt; M Fornerod; R Zwart; R D Schneiderman; G Grosveld; A W Nienhuis
Journal:  Hum Gene Ther       Date:  1995-09       Impact factor: 5.695

7.  Foamy virus vectors.

Authors:  D W Russell; A D Miller
Journal:  J Virol       Date:  1996-01       Impact factor: 5.103

8.  Human foamy virus replication: a pathway distinct from that of retroviruses and hepadnaviruses.

Authors:  S F Yu; D N Baldwin; S R Gwynn; S Yendapalli; M L Linial
Journal:  Science       Date:  1996-03-15       Impact factor: 47.728

Review 9.  Unexpected replication pathways of foamy viruses.

Authors:  A Rethwilm
Journal:  J Acquir Immune Defic Syndr Hum Retrovirol       Date:  1996

10.  Foamy virus reverse transcriptase is expressed independently from the Gag protein.

Authors:  J Enssle; I Jordan; B Mauer; A Rethwilm
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-30       Impact factor: 11.205
View more
  42 in total

1.  Complex effects of deletions in the 5' untranslated region of primate foamy virus on viral gene expression and RNA packaging.

Authors:  M Heinkelein; J Thurow; M Dressler; H Imrich; D Neumann-Haefelin; M O McClure; A Rethwilm
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

2.  Use of a transient assay for studying the genetic determinants of Fv1 restriction.

Authors:  M Bock; K N Bishop; G Towers; J P Stoye
Journal:  J Virol       Date:  2000-08       Impact factor: 5.103

3.  Foamy virus envelope glycoprotein-mediated entry involves a pH-dependent fusion process.

Authors:  Marcus Picard-Maureau; Gergely Jarmy; Angelika Berg; Axel Rethwilm; Dirk Lindemann
Journal:  J Virol       Date:  2003-04       Impact factor: 5.103

4.  Intracellular trafficking of Gag and Env proteins and their interactions modulate pseudotyping of retroviruses.

Authors:  Virginie Sandrin; Delphine Muriaux; Jean-Luc Darlix; François-Loïc Cosset
Journal:  J Virol       Date:  2004-07       Impact factor: 5.103

Review 5.  Molecular biology of foamy viruses.

Authors:  Axel Rethwilm
Journal:  Med Microbiol Immunol       Date:  2010-05-06       Impact factor: 3.402

6.  Novel functions of prototype foamy virus Gag glycine- arginine-rich boxes in reverse transcription and particle morphogenesis.

Authors:  Erik Müllers; Tobias Uhlig; Kristin Stirnnagel; Uwe Fiebig; Hanswalter Zentgraf; Dirk Lindemann
Journal:  J Virol       Date:  2010-11-24       Impact factor: 5.103

7.  An envelope glycoprotein of the human endogenous retrovirus HERV-W is expressed in the human placenta and fuses cells expressing the type D mammalian retrovirus receptor.

Authors:  J L Blond; D Lavillette; V Cheynet; O Bouton; G Oriol; S Chapel-Fernandes; B Mandrand; F Mallet; F L Cosset
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

8.  Prototype foamy virus envelope glycoprotein leader peptide processing is mediated by a furin-like cellular protease, but cleavage is not essential for viral infectivity.

Authors:  Anja Duda; Annett Stange; Daniel Lüftenegger; Nicole Stanke; Dana Westphal; Thomas Pietschmann; Scott W Eastman; Maxine L Linial; Axel Rethwilm; Dirk Lindemann
Journal:  J Virol       Date:  2004-12       Impact factor: 5.103

9.  Characterization of prototype foamy virus gag late assembly domain motifs and their role in particle egress and infectivity.

Authors:  Annett Stange; Ingrid Mannigel; Katrin Peters; Martin Heinkelein; Nicole Stanke; Marc Cartellieri; Heinrich Göttlinger; Axel Rethwilm; Hanswalter Zentgraf; Dirk Lindemann
Journal:  J Virol       Date:  2005-05       Impact factor: 5.103

10.  Correct capsid assembly mediated by a conserved YXXLGL motif in prototype foamy virus Gag is essential for infectivity and reverse transcription of the viral genome.

Authors:  Ingrid Mannigel; Annett Stange; Hanswalter Zentgraf; Dirk Lindemann
Journal:  J Virol       Date:  2007-01-17       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.