Literature DB >> 9150238

Antimonite is accumulated by the glycerol facilitator GlpF in Escherichia coli.

O I Sanders1, C Rensing, M Kuroda, B Mitra, B P Rosen.   

Abstract

In a search for genes responsible for the accumulation of antimonite in Escherichia coli, TnphoA was used to create a pool of random insertional mutants, from which one antimonite-resistant mutant was isolated. Sequence analysis showed that the TnphoA insertion was located in the glpF gene, coding for the glycerol facilitator GlpF. The mutant was shown to be defective in polyol transport by GlpF. These results suggest that in solution Sb(III) is recognized as a polyol by the glycerol facilitator.

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Year:  1997        PMID： 9150238      PMCID： PMC179121          DOI： 10.1128/jb.179.10.3365-3367.1997

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  13 in total

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