Literature DB >> 914862

Structural study of circulating thymic factor: a peptide isolated from pig serum. II. Amino acid sequence.

J M Pleau, M Dardenne, Y Blouquit, J F Bach.   

Abstract

The amino acid sequence of a circulating thymic factor (FTS, facteur thymique sérique) isolated from pig serum has been established as less than Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH. This sequence was obtained by Edman analysis both on the intact peptide and after tryptic digestion. The COOH-terminal residue was identified by carboxypeptidase A digestion. A synthetic peptide was prepared which showed the same biological activities as native pig circulating thymic factor, thus confirming the proposed primary structure.

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Year:  1977        PMID: 914862

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  17 in total

Review 1.  Thymulin, a zinc-dependent hormone.

Authors:  J F Bach; M Dardenne
Journal:  Med Oncol Tumor Pharmacother       Date:  1989

2.  A zinc-dependent epitope on the molecule of thymulin, a thymic hormone.

Authors:  M Dardenne; W Savino; S Berrih; J F Bach
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205

3.  Neonatal thymus grafts. I. Studies on the regulation of the level of circulating thymic factor (FTS).

Authors:  N Tubiana; M Dardenne
Journal:  Immunology       Date:  1979-02       Impact factor: 7.397

4.  Preparations of homeostatic thymus hormone consist predominantly of histones 2A and 2B and suggest additional histone functions.

Authors:  R Reichhart; M Zeppezauer; H Jörnvall
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

5.  Thymopentin structure and relation to thymic factors.

Authors:  G A Heavner
Journal:  Surv Immunol Res       Date:  1985

6.  Common antigenicity between a human thymic epithelial cell product and a thymus-dependent serum factor.

Authors:  E F Potworowski; D Kowalczyk; V V Micusan; T Seemayer
Journal:  Experientia       Date:  1982-07-15

7.  The serum thymic factor (FTS). Chemical and biological aspects.

Authors:  J M Pleau; M Dardenne; J F Bach
Journal:  Mol Cell Biochem       Date:  1981-12-04       Impact factor: 3.396

8.  Thymic hormone containing cells. II. Evolution of cells containing the serum thymic factor (FTS or thymulin) in normal and autoimmune mice, as revealed by anti-FTS monoclonal antibodies. Relationship with Ia bearing cells.

Authors:  W Savino; M Dardenne; J F Bach
Journal:  Clin Exp Immunol       Date:  1983-04       Impact factor: 4.330

9.  Isolation and characterization of DNA-binding peptides from the serum: inhibition of transcription and comparison with the tissue peptides.

Authors:  D Amici; D Barra; M Hillar; O Murri; F Cicconi; G L Gianfranceschi
Journal:  Mol Biol Rep       Date:  1982-11-30       Impact factor: 2.316

10.  In vitro induction of monoclonal antibody-defined T-cell markers in lymphocytes from immunodeficient children by synthetic serum thymic factor (FTS).

Authors:  M C Bene; G Faure; P Bordigoni; D Olive; J Duheille
Journal:  Clin Exp Immunol       Date:  1982-05       Impact factor: 4.330

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