Literature DB >> 9147496

Proton magnetic resonance spectroscopy of the temporal lobes in schizophrenics and normal controls.

D A Yurgelun-Todd1, P F Renshaw, S A Gruber, M Ed, C Waternaux, B M Cohen.   

Abstract

Previous research has found structural and functional abnormalities in the temporal lobes of schizophrenic patients, often with greater impairment on the left side. This study applied proton MRS to both right and left temporal lobes of schizophrenic patients and normal control subjects. Reductions in the NAA/Cr ratio were found bilaterally for schizophrenic patients as compared to normal controls, and may be associated with reduced neuronal integrity. These results strengthen the evidence for biochemical abnormalities in the temporal lobes in schizophrenia.

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Year:  1996        PMID: 9147496     DOI: 10.1016/0920-9964(95)00071-2

Source DB:  PubMed          Journal:  Schizophr Res        ISSN: 0920-9964            Impact factor:   4.939


  11 in total

Review 1.  Neurometabolites in schizophrenia and bipolar disorder - a systematic review and meta-analysis.

Authors:  Nina Vanessa Kraguljac; Meredith Reid; David White; Rebecca Jones; Jan den Hollander; Deborah Lowman; Adrienne Carol Lahti
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Review 2.  Modeling psychiatric disorders at the cellular and network levels.

Authors:  K J Brennand; A Simone; N Tran; F H Gage
Journal:  Mol Psychiatry       Date:  2012-04-03       Impact factor: 15.992

Review 3.  Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia.

Authors:  Hayley B Clay; Stephanie Sillivan; Christine Konradi
Journal:  Int J Dev Neurosci       Date:  2010-09-15       Impact factor: 2.457

Review 4.  Creatine metabolism and psychiatric disorders: Does creatine supplementation have therapeutic value?

Authors:  Patricia J Allen
Journal:  Neurosci Biobehav Rev       Date:  2012-03-24       Impact factor: 8.989

Review 5.  [Magnetic resonance spectroscopy in schizophrenia. Possibilities and limitations].

Authors:  T Wobrock; H Scherk; P Falkai
Journal:  Radiologe       Date:  2005-02       Impact factor: 0.635

6.  Magnetic resonance imaging and spectroscopy in a mouse model of schizophrenia.

Authors:  German Torres; Brian H Hallas; Kenneth W Gross; Joseph A Spernyak; Judith M Horowitz
Journal:  Brain Res Bull       Date:  2007-10-17       Impact factor: 4.077

Review 7.  1H MR spectroscopy in patients with mesial temporal epilepsy.

Authors:  M Hájek; M Dezortová; V Komárek
Journal:  MAGMA       Date:  1998-12       Impact factor: 2.310

8.  The biochemical womb of schizophrenia: A review.

Authors:  N Gaur; S Gautam; M Gaur; P Sharma; G Dadheech; S Mishra
Journal:  Indian J Clin Biochem       Date:  2008-12-20

Review 9.  T2 relaxation effects on apparent N-acetylaspartate concentration in proton magnetic resonance studies of schizophrenia.

Authors:  Bethany K Bracken; Elizabeth D Rouse; Perry F Renshaw; David P Olson
Journal:  Psychiatry Res       Date:  2013-06-12       Impact factor: 3.222

10.  In vivo investigation of white matter pathology in schizophrenia with magnetisation transfer imaging.

Authors:  J Foong; M Maier; G J Barker; S Brocklehurst; D H Miller; M A Ron
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-01       Impact factor: 10.154

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