Literature DB >> 23105779

The biochemical womb of schizophrenia: A review.

N Gaur1, S Gautam, M Gaur, P Sharma, G Dadheech, S Mishra.   

Abstract

The conclusive identification of specific etiological factors or pathogenic processes in the illness of schizophrenia has remained elusive despite great technological progress. The convergence of state-of-art scientific studies in molecular genetics, molecular neuropathophysiology, in vivo brain imaging and psychopharmacology, however, indicates that we may be coming much closer to understanding the genesis of schizophrenia. In near future, the diagnosis and assessment of schizophrenia using biochemical markers may become a "dream come true" for the medical community as well as for the general population. An understanding of the biochemistry/ visa vis pathophysiology of schizophrenia is essential to the discovery of preventive measures and therapeutic intervention.

Entities:  

Keywords:  Biochemical markers; Neurobiology; Schizophrenia

Year:  2008        PMID: 23105779      PMCID: PMC3453132          DOI: 10.1007/s12291-008-0071-x

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN: 0970-1915


  212 in total

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Authors:  A Jablensky; N Sartorius; G Ernberg; M Anker; A Korten; J E Cooper; R Day; A Bertelsen
Journal:  Psychol Med Monogr Suppl       Date:  1992

Review 2.  Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia.

Authors:  A A Grace
Journal:  Neuroscience       Date:  1991       Impact factor: 3.590

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Authors:  P J Harrison; D McLaughlin; R W Kerwin
Journal:  Lancet       Date:  1991-02-23       Impact factor: 79.321

4.  Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons.

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Journal:  Science       Date:  1975-06-20       Impact factor: 47.728

5.  Hypothalamic-pituitary-adrenal axis hyperactivity and psychosis: recovery during an 8-year follow-up.

Authors:  W Coryell; D Tsuang
Journal:  Am J Psychiatry       Date:  1992-08       Impact factor: 18.112

6.  The incidence of abnormal dexamethasone suppression in schizophrenia: a review and a meta-analytic comparison with the incidence in normal controls.

Authors:  V K Yeragani
Journal:  Can J Psychiatry       Date:  1990-03       Impact factor: 4.356

7.  Neurosteroid regulation of GABAA receptor single-channel kinetic properties of mouse spinal cord neurons in culture.

Authors:  R E Twyman; R L Macdonald
Journal:  J Physiol       Date:  1992-10       Impact factor: 5.182

Review 8.  Neuroactive steroids.

Authors:  S M Paul; R H Purdy
Journal:  FASEB J       Date:  1992-03       Impact factor: 5.191

9.  Blood protein fraction comparisons of normal and schizophrenic patients.

Authors:  E F Domino; R R Krause; M M Thiessen; J G Batsakis
Journal:  Arch Gen Psychiatry       Date:  1975-06

10.  3,4-Dihydroxyphenylacetic acid and homovanillic acid in rat plasma: possible indicators of central dopaminergic activity.

Authors:  N G Bacopoulos; S E Hattox; R H Roth
Journal:  Eur J Pharmacol       Date:  1979-06-15       Impact factor: 4.432

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  5 in total

1.  Metabolic issues in schizophrenic patients receiving antipsychotic treatment.

Authors:  Aditi Gupta; Gora Dadheech; Dharamveer Yadav; Praveen Sharma; Shiv Gautam
Journal:  Indian J Clin Biochem       Date:  2014-01-23

Review 2.  Β-Amyloid Burden is Not Associated with Cognitive Impairment in Schizophrenia: A Systematic Review.

Authors:  Jun Ku Chung; Shinichiro Nakajima; Eric Plitman; Yusuke Iwata; Danielle Uy; Philip Gerretsen; Fernando Caravaggio; M Mallar Chakravarty; Ariel Graff-Guerrero
Journal:  Am J Geriatr Psychiatry       Date:  2016-04-29       Impact factor: 4.105

Review 3.  Vitamin C in disease prevention and cure: an overview.

Authors:  Shailja Chambial; Shailendra Dwivedi; Kamla Kant Shukla; Placheril J John; Praveen Sharma
Journal:  Indian J Clin Biochem       Date:  2013-09-01

4.  Repeated Clozapine Increases the Level of Serotonin 5-HT1AR Heterodimerization with 5-HT2A or Dopamine D2 Receptors in the Mouse Cortex.

Authors:  Marta Szlachta; Maciej Kuśmider; Paulina Pabian; Joanna Solich; Magdalena Kolasa; Dariusz Żurawek; Marta Dziedzicka-Wasylewska; Agata Faron-Górecka
Journal:  Front Mol Neurosci       Date:  2018-02-15       Impact factor: 5.639

5.  Toxoplasma infection in male mice alters dopamine-sensitive behaviors and host gene expression patterns associated with neuropsychiatric disease.

Authors:  Graham L Cromar; Jonathan R Epp; Ana Popovic; Yusing Gu; Violet Ha; Brandon J Walters; James St Pierre; Xuejian Xiong; John G Howland; Sheena A Josselyn; Paul W Frankland; John Parkinson
Journal:  PLoS Negl Trop Dis       Date:  2022-07-20
  5 in total

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